Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes | |
Wang, X. ; Jia, G. ; Wang, H. ; Nie, H. ; Yan, L. ; Deng, X. Y. ; Wang, S. | |
刊名 | journal of nanoscience and nanotechnology |
2009 | |
关键词 | Cytotoxicity Alveolar Macrophages (AM) Diameter-Effect Apoptosis Multi-Walled Carbon Nanotubes (MWNTs) IN-VIVO PULMONARY TOXICITY CELLS MICE BIODISTRIBUTION NANOMATERIALS ASSAYS |
DOI | 10.1166/jnn.2009.025 |
英文摘要 | In this work, we focus on the diameter effects on cytotoxicity of different diametered multi-walled carbon nanotubes (MWNTs). Cellular viability, phagocytotic ability, and apoptosis of guinea pig alveolar macrophages (AM) exposed to MWNTs were studied. MWNTs in smaller diameter showed less cytotoxicity than the larger ones at the same dosage. The phagocytosis ability of AM was partially impaired when the concentration of MWNTs was up to 20 mu g/ml, where a further characteristic feature of AM apoptosis was observed. The results indicate that MWNTs in different diameters exhibited quite different cytotoxicity, and for the first time revealed the diameter-effect of MWNTs on cytotoxicity.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000265186800033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter; SCI(E); EI; PubMed; 51; ARTICLE; 5; 3025-3033; 9 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/344976] |
专题 | 化学与分子工程学院 |
推荐引用方式 GB/T 7714 | Wang, X.,Jia, G.,Wang, H.,et al. Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes[J]. journal of nanoscience and nanotechnology,2009. |
APA | Wang, X..,Jia, G..,Wang, H..,Nie, H..,Yan, L..,...&Wang, S..(2009).Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes.journal of nanoscience and nanotechnology. |
MLA | Wang, X.,et al."Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes".journal of nanoscience and nanotechnology (2009). |
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