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Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes
Wang, X. ; Jia, G. ; Wang, H. ; Nie, H. ; Yan, L. ; Deng, X. Y. ; Wang, S.
刊名journal of nanoscience and nanotechnology
2009
关键词Cytotoxicity Alveolar Macrophages (AM) Diameter-Effect Apoptosis Multi-Walled Carbon Nanotubes (MWNTs) IN-VIVO PULMONARY TOXICITY CELLS MICE BIODISTRIBUTION NANOMATERIALS ASSAYS
DOI10.1166/jnn.2009.025
英文摘要In this work, we focus on the diameter effects on cytotoxicity of different diametered multi-walled carbon nanotubes (MWNTs). Cellular viability, phagocytotic ability, and apoptosis of guinea pig alveolar macrophages (AM) exposed to MWNTs were studied. MWNTs in smaller diameter showed less cytotoxicity than the larger ones at the same dosage. The phagocytosis ability of AM was partially impaired when the concentration of MWNTs was up to 20 mu g/ml, where a further characteristic feature of AM apoptosis was observed. The results indicate that MWNTs in different diameters exhibited quite different cytotoxicity, and for the first time revealed the diameter-effect of MWNTs on cytotoxicity.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000265186800033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Multidisciplinary; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter; SCI(E); EI; PubMed; 51; ARTICLE; 5; 3025-3033; 9
语种英语
内容类型期刊论文
源URL[http://ir.pku.edu.cn/handle/20.500.11897/344976]  
专题化学与分子工程学院
推荐引用方式
GB/T 7714
Wang, X.,Jia, G.,Wang, H.,et al. Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes[J]. journal of nanoscience and nanotechnology,2009.
APA Wang, X..,Jia, G..,Wang, H..,Nie, H..,Yan, L..,...&Wang, S..(2009).Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes.journal of nanoscience and nanotechnology.
MLA Wang, X.,et al."Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes".journal of nanoscience and nanotechnology (2009).
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