Copper-Catalyzed Direct Ortho-Alkylation of N-Iminopyridinium Ylides   with N-Tosylhydrazones

doi:10.1021/jo4002883

CORC > 北京大学 > 化学与分子工程学院

	Copper-Catalyzed Direct Ortho-Alkylation of N-Iminopyridinium Ylides with N-Tosylhydrazones
	Xiao, Qing ; Ling, Lin ; Ye, Fei ; Tan, Renchang ; Tian, Leiming ; Zhang, Yan ; Li, Yuxue ; Wang, Jianbo
刊名	journal of organic chemistry
	2013
关键词	C-H ARYLATION NICKEL/LEWIS ACID CATALYSIS CROSS-COUPLING REACTIONS SELECTIVE ALKENYLATION BOND FUNCTIONALIZATION AROMATIC HETEROCYCLES INSERTION CHEMISTRY PYRIDINE OXIDES COMPLEXES
DOI	10.1021/jo4002883
英文摘要	Copper-catalyzed cross-coupling of N-tosylhydrazones with N-iminopyridinium ylides leads to the direct C-H alkylation. This direct C-H bond alkylation transformation uses inexpensive CuI as the catalyst without any ligand. The reaction is operationally simple and conducted under mild conditions, giving the corresponding alkylated pyridines in moderate to good yields. DFT calculation provides insights into the reaction mechanism, suggesting that the reaction proceeds through the Cu carbene migratory insertion process.; Chemistry, Organic; SCI(E); PubMed; 28; ARTICLE; 8; 3879-3885; 78
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/342777]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Xiao, Qing,Ling, Lin,Ye, Fei,et al. Copper-Catalyzed Direct Ortho-Alkylation of N-Iminopyridinium Ylides with N-Tosylhydrazones[J]. journal of organic chemistry,2013.
APA	Xiao, Qing.,Ling, Lin.,Ye, Fei.,Tan, Renchang.,Tian, Leiming.,...&Wang, Jianbo.(2013).Copper-Catalyzed Direct Ortho-Alkylation of N-Iminopyridinium Ylides with N-Tosylhydrazones.journal of organic chemistry.
MLA	Xiao, Qing,et al."Copper-Catalyzed Direct Ortho-Alkylation of N-Iminopyridinium Ylides with N-Tosylhydrazones".journal of organic chemistry (2013).