Cu(I)-Catalyzed Cross-Coupling of Terminal Alkynes with Trifluoromethyl Ketone N-Tosylhydrazones: Access to 1,1-Difluoro-1,3-enynes

doi:10.1021/acs.orglett.5b00980

CORC > 北京大学 > 化学与分子工程学院

	Cu(I)-Catalyzed Cross-Coupling of Terminal Alkynes with Trifluoromethyl Ketone N-Tosylhydrazones: Access to 1,1-Difluoro-1,3-enynes
	Zhang Zhikun ; Zhou Qi ; Yu Weizhi ; Li Tianjiao ; Wu Guojiao ; Zhang Yan ; Wang Jianbo
刊名	organic letters
	2015
DOI	10.1021/acs.orglett.5b00980
英文摘要	C-C Bond formation and β-F elimination have been achieved in a Cu(I)-catalyzed cross-coupling reaction of terminal alkynes and trifluoromethyl ketone N-tosylhydrazones. The reaction represents an efficient synthesis of 1,1-difluoro-1,3-enyne derivatives. Mechanistically, the migratory insertion of the copper carbene intermediate leads to the C-C bond formation, which is followed by C-F bond cleavage.; SCI(E); PubMed; 0; ARTICLE; wangjb@pku.edu.cn
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/341239]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Zhang Zhikun,Zhou Qi,Yu Weizhi,et al. Cu(I)-Catalyzed Cross-Coupling of Terminal Alkynes with Trifluoromethyl Ketone N-Tosylhydrazones: Access to 1,1-Difluoro-1,3-enynes[J]. organic letters,2015.
APA	Zhang Zhikun.,Zhou Qi.,Yu Weizhi.,Li Tianjiao.,Wu Guojiao.,...&Wang Jianbo.(2015).Cu(I)-Catalyzed Cross-Coupling of Terminal Alkynes with Trifluoromethyl Ketone N-Tosylhydrazones: Access to 1,1-Difluoro-1,3-enynes.organic letters.
MLA	Zhang Zhikun,et al."Cu(I)-Catalyzed Cross-Coupling of Terminal Alkynes with Trifluoromethyl Ketone N-Tosylhydrazones: Access to 1,1-Difluoro-1,3-enynes".organic letters (2015).