New Methods and Techniques for F-18-Labeled Radiopharmaceuticals

CORC > 北京大学 > 化学与分子工程学院

	New Methods and Techniques for F-18-Labeled Radiopharmaceuticals
	Huang Huafan ; Liang Kun ; Liu Yupeng ; Huang Shitang ; Chu Taiwei
刊名	化学进展
	2011
关键词	radiopharmaceutical chemistry labeling boronic ester microfluidic fluoro-18 POSITRON-EMISSION-TOMOGRAPHY CLICK CHEMISTRY FLUOROUS SYNTHESIS DETAGGING PROCESS PEPTIDES PET GLYCOSYLATION RADIOTRACERS REACTORS
英文摘要	The availability of radiopharmaceuticals is one prerequisite for positron emission tomography (PET) investigation. F-18 appears to be the best candidate among a number of positron emission nuclides. Nevertheless, the chemistry of fluorine limits F-18 labeled strategies, and the preparation of many F-labeled radiopharmaceuticals is still laborious and time-consuming. In this review, new F-18-labeling methods and techniques in radiopharmaceutical chemistry are described, including detagging F-18-labeling methodology, direct radiolabeling of peptides with [F-18] FDG, Al F-18-chelated labeling, aqueous F-18-labeling of boronic esters, microfluidics-based radiochemical synthesis technologies for PET probes and so on. This review will provide an overview in new F-18-labeling methods and techniques for related researchers.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000293676100026&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Multidisciplinary; SCI(E); 中文核心期刊要目总览(PKU); 中国科技核心期刊(ISTIC); 6; ARTICLE; 7,SI; 1501-1506; 23
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/313151]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Huang Huafan,Liang Kun,Liu Yupeng,et al. New Methods and Techniques for F-18-Labeled Radiopharmaceuticals[J]. 化学进展,2011.
APA	Huang Huafan,Liang Kun,Liu Yupeng,Huang Shitang,&Chu Taiwei.(2011).New Methods and Techniques for F-18-Labeled Radiopharmaceuticals.化学进展.
MLA	Huang Huafan,et al."New Methods and Techniques for F-18-Labeled Radiopharmaceuticals".化学进展 (2011).