Molecularly imprinted polymer for pyrazinamide

doi:10.1081/AL-120021532

CORC > 北京大学 > 化学与分子工程学院

	Molecularly imprinted polymer for pyrazinamide
	Sun, BW ; Li, YZ ; Chang, WB
刊名	analytical letters
	2003
关键词	molecularly imprinted polymer pyrazinamide pyrazine solvent effect chromatographic separation BINDING ASSAY TUBERCULOSIS SENSOR
DOI	10.1081/AL-120021532
英文摘要	Pyrazinamide (PZA) is one of the most widely used antitubercular drugs. In this study a polymer selective for pyrazinamide was synthesized by a molecular imprinting technique, and the binding characteristics of the imprinted polymer (MIP) were studied by high performance liquid chromatography. When the mobile phase was the same as the solvent used in polymerization, the most obvious imprinting effect was obtained. Though the molecular weight of the template is low, the imprinted polymer showed selectivity for PZA over its analogues. The mixture of PZA and pyrazine (or nicotinamide) was separated on a column packed with imprinted polymer, while it was unable to be separated on the column packed with non-imprinted polymer.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183990000004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Analytical; SCI(E); 7; ARTICLE; 8; 1501-1509; 36
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/256237]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Sun, BW,Li, YZ,Chang, WB. Molecularly imprinted polymer for pyrazinamide[J]. analytical letters,2003.
APA	Sun, BW,Li, YZ,&Chang, WB.(2003).Molecularly imprinted polymer for pyrazinamide.analytical letters.
MLA	Sun, BW,et al."Molecularly imprinted polymer for pyrazinamide".analytical letters (2003).