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Biodistribution of pristine single-walled carbon nanotubes in vivo
Yang, Sheng-Tao ; Guo, Wei ; Lin, Yi ; Deng, Xiao-Yong ; Wang, Hai-Fang ; Sun, Hong-Fang ; Liu, Yuan-Fang ; Wang, Xin ; Wang, Wei ; Chen, Min ; Huang, Yi-Pu ; Sun, Ya-Ping
刊名journal of physical chemistry c
2007
关键词TOXICITY BLOOD MICROSPHERES CLEARANCE TISSUE BRAIN RATS
DOI10.1021/jp070712c
英文摘要The biodistribution of pristine single-walled carbon nanotubes (SWNTs) in mice was determined by using the skeleton C-13-enriched SWNTs and isotope ratio mass spectroscopy. The results suggested that the SWNTs were distributed in the entire body, with major accumulations in the liver, lungs, and spleen over an extended period of time. The specimen from the effected organ tissues were examined by using transmission electron microscopy, aimed toward an understanding of the possible uptake mechanism. The biological consequence of pristine SWNTs is obviously very different from that of their chemically modified or functionalized counterparts. The implication of such a fact is discussed.; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; SCI(E); EI; 0; ARTICLE; 48; 17761-17764; 111
语种英语
内容类型期刊论文
源URL[http://ir.pku.edu.cn/handle/20.500.11897/250665]  
专题化学与分子工程学院
推荐引用方式
GB/T 7714
Yang, Sheng-Tao,Guo, Wei,Lin, Yi,et al. Biodistribution of pristine single-walled carbon nanotubes in vivo[J]. journal of physical chemistry c,2007.
APA Yang, Sheng-Tao.,Guo, Wei.,Lin, Yi.,Deng, Xiao-Yong.,Wang, Hai-Fang.,...&Sun, Ya-Ping.(2007).Biodistribution of pristine single-walled carbon nanotubes in vivo.journal of physical chemistry c.
MLA Yang, Sheng-Tao,et al."Biodistribution of pristine single-walled carbon nanotubes in vivo".journal of physical chemistry c (2007).
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