Albumin-conjugated Cadmium Sulfide Nanoparticles and their Interaction   with KB Cells

CORC > 北京大学 > 化学与分子工程学院

	Albumin-conjugated Cadmium Sulfide Nanoparticles and their Interaction with KB Cells
	Selim, K. M. Kamruzzaman ; Kang, Inn-Kyu ; Guo, Haiqing
刊名	macromolecular research
	2009
关键词	cadmium sulfide nanoparticles bovine serum albumin biocompatibility fluorescence intensity SEMICONDUCTOR QUANTUM DOTS BOVINE SERUM-ALBUMIN CDS NANOPARTICLES SURFACE MODIFICATION AQUEOUS-SOLUTION IN-VIVO NANOCRYSTALS PROTEIN NANOCOMPOSITES
英文摘要	Cytotoxicity is a severe problem of cadmium sulfide nanoparticles (CSNPs) for use in biological systems. In the present study, mercaptoacetic acid-coated CSNPs were conjugated with bovine serum albumin (BSA) to improve biocompatibility. The surface properties of the CSNPs and albumin-conjugated CSNPs (ACSNPs) were characterized by XRD, UV, FTIR, EA, TEM and DLS. Human breast cancer cells (KB cells) were then cultured in the presence of the nanoparticles to evaluate the cytotoxicity of CSNPs and ACSNPs. Finally, the fluorescence intensity of the nanoparticles' aqueous solution was examined using a fluorescence spectrometer. The results showed that the cell compatibility and fluorescence intensity of ACSNPs were higher than those of CSNPs. The strongly luminescent features of the biocompatible ACSNPs are promising for use in biological fields such as cellular labeling, intracellular tracking and molecular imaging.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000267857800005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Polymer Science; SCI(E); 11; ARTICLE; 6; 403-410; 17
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/245790]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Selim, K. M. Kamruzzaman,Kang, Inn-Kyu,Guo, Haiqing. Albumin-conjugated Cadmium Sulfide Nanoparticles and their Interaction with KB Cells[J]. macromolecular research,2009.
APA	Selim, K. M. Kamruzzaman,Kang, Inn-Kyu,&Guo, Haiqing.(2009).Albumin-conjugated Cadmium Sulfide Nanoparticles and their Interaction with KB Cells.macromolecular research.
MLA	Selim, K. M. Kamruzzaman,et al."Albumin-conjugated Cadmium Sulfide Nanoparticles and their Interaction with KB Cells".macromolecular research (2009).