Solution behavior of copolymers with poly(ethylene oxide) as the   &quot;hydrophobic&quot; block

doi:10.1039/c1sm05963g

CORC > 北京大学 > 化学与分子工程学院

	Solution behavior of copolymers with poly(ethylene oxide) as the "hydrophobic" block
	Zhou, Jihan ; Ke, Fuyou ; Tong, Yin-yin ; Li, Zi-chen ; Liang, Dehai
刊名	软性材料
	2011
关键词	DYNAMIC LIGHT-SCATTERING DRUG-DELIVERY AGGREGATION BEHAVIOR POLYMERIC MICELLES AQUEOUS-SOLUTION WATER-STRUCTURE HYDROGELS POLY(N-ISOPROPYLACRYLAMIDE) ASSOCIATION STABILITY
DOI	10.1039/c1sm05963g
英文摘要	Block copolymers containg poly(ethylene oxide) (PEO) have been widely used in biomedical applications. The PEO block is generally treated as the hydrophilic moiety. In this work, we demonstrated that PEO could serve as the "hydrophobic'' block under certain conditions by using PEO-b-poly(vinyl alcohol) (PEO-b-PVA) as the example. Water is a non-selective solvent for both of the blocks, however, the addition of NaCl decreases the solubility of PEO in aqueous solution while it shows no effect on the PVA block. With the solubility of PEO being deteriorated by adding NaCl, PEO-b-PVA exhibited amphiphilic feature in aqueous solution with PEO being the "hydrophobic'' block. Therefore, by just adding salts, uniform gel-like particles were formed by PEO-b-PVA of proper block ratio. These solid particles formed by dual hydrophilic copolymers with excellent biocompability may have great potential in biomedical applications.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000296026700022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Physical; Materials Science, Multidisciplinary; Physics, Multidisciplinary; Polymer Science; SCI(E); EI; 7; ARTICLE; 21; 9956-9961; 7
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/243673]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Zhou, Jihan,Ke, Fuyou,Tong, Yin-yin,et al. Solution behavior of copolymers with poly(ethylene oxide) as the "hydrophobic" block[J]. 软性材料,2011.
APA	Zhou, Jihan,Ke, Fuyou,Tong, Yin-yin,Li, Zi-chen,&Liang, Dehai.(2011).Solution behavior of copolymers with poly(ethylene oxide) as the "hydrophobic" block.软性材料.
MLA	Zhou, Jihan,et al."Solution behavior of copolymers with poly(ethylene oxide) as the "hydrophobic" block".软性材料 (2011).