Ir-catalyzed highly selective addition of pyridyl C-H bonds to aldehydes   promoted by triethylsilane

doi:10.1039/c0sc00419g

CORC > 北京大学 > 化学与分子工程学院

	Ir-catalyzed highly selective addition of pyridyl C-H bonds to aldehydes promoted by triethylsilane
	Li, Bi-Jie ; Shi, Zhang-Jie
刊名	chemical science
	2011
关键词	INTERMOLECULAR DIRECT ARYLATION NICKEL/LEWIS ACID CATALYSIS DIRECTED ORTHO-METALATION N-IMINOPYRIDINIUM YLIDES CARBON-HYDROGEN BONDS HETEROAROMATIC-COMPOUNDS UNSATURATED MOLECULES AROMATIC HETEROCYCLES IRIDIUM COMPLEXES ORGANIC-SYNTHESIS
DOI	10.1039/c0sc00419g
英文摘要	We report herein an iridium-catalyzed activation of pyridine C-H bond and its nucleophilic addition to benzaldehydes. The reaction was applicable to various pyridine derivatives and aryl aldehydes. In contrast to most methods that selectively functionalize the C2 pyridine C-H bond, this reaction proceeded with unusual meta-selectivity. An independently synthesized silyl iridium complex was able to catalyze the reaction, indicating that a silyl iridium intermediate might be responsible for the novel reactivity and the unusual selectivity.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000287364400016&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Multidisciplinary; SCI(E); 83; 3; 488-493; 2
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/241087]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Li, Bi-Jie,Shi, Zhang-Jie. Ir-catalyzed highly selective addition of pyridyl C-H bonds to aldehydes promoted by triethylsilane[J]. chemical science,2011.
APA	Li, Bi-Jie,&Shi, Zhang-Jie.(2011).Ir-catalyzed highly selective addition of pyridyl C-H bonds to aldehydes promoted by triethylsilane.chemical science.
MLA	Li, Bi-Jie,et al."Ir-catalyzed highly selective addition of pyridyl C-H bonds to aldehydes promoted by triethylsilane".chemical science (2011).