Separation of the enantiomers of four chiral drugs by neutral   cyclodextrin-mediated capillary zone electrophoresis

doi:10.1007/BF02467615

CORC > 北京大学 > 化学与分子工程学院

	Separation of the enantiomers of four chiral drugs by neutral cyclodextrin-mediated capillary zone electrophoresis
	Ren, XQ ; Dong, YY ; Huang, AJ ; Sun, YL ; Sun, ZP
刊名	chromatographia
	1999
关键词	capillary electrophoresis chiral separation neutral cyclodextrins clorprenaline and other chiral drugs PSEUDO-STATIONARY PHASES ELECTROKINETIC CHROMATOGRAPHY DERIVATIVES RESOLUTION AGENT
DOI	10.1007/BF02467615
英文摘要	Neutral cyclodextrin (CD)-modified capillary zone electrophoresis (CZE) has been applied to the chiral separation of four basic drugs - clorprenaline, benzhexol, esmolol and terazosin. Selector screening and concentration optimization experiments were performed. The resolution was 3.9 for clorprenaline, 2.3 for benzhexol, 3.1 for esmolol and 1.2 for terazosin when the running electrolyte was 60 mM hydroxypropyl-beta-CD, 15 mM heptakis (2,3,6-Tri-O-methyl)-beta-CD, 60 mM gamma-CD and 60 mM heptakis (2,6-di-O-methyl)-beta-CD, respectively, in 50 mM, pH 2.5 sodium phosphate buffer.; Biochemical Research Methods; Chemistry, Analytical; SCI(E); 7; ARTICLE; 7-8; 411-414; 49
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/214456]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Ren, XQ,Dong, YY,Huang, AJ,et al. Separation of the enantiomers of four chiral drugs by neutral cyclodextrin-mediated capillary zone electrophoresis[J]. chromatographia,1999.
APA	Ren, XQ,Dong, YY,Huang, AJ,Sun, YL,&Sun, ZP.(1999).Separation of the enantiomers of four chiral drugs by neutral cyclodextrin-mediated capillary zone electrophoresis.chromatographia.
MLA	Ren, XQ,et al."Separation of the enantiomers of four chiral drugs by neutral cyclodextrin-mediated capillary zone electrophoresis".chromatographia (1999).