Molecularly imprinted polymers from nicotinamide and its positional   isomers

doi:10.1002/jmr.526

CORC > 北京大学 > 化学与分子工程学院

	Molecularly imprinted polymers from nicotinamide and its positional isomers
	Fu, Q ; Zheng, N ; Li, YZ ; Chang, WB ; Wang, ZM
刊名	分子识别杂志
	2001
关键词	molecular imprinting nicotinamide positional isomer separation polymer isonicotinamide picolinamide CHIRAL SEPARATION RECOGNITION PYRIDOXINE ADSORBENTS
DOI	10.1002/jmr.526
英文摘要	Imprinted polymers were prepared for nicotinamide and its positional isomers, The influence of porogenic solvent and functional monomer on recognition properties of the polymer was compared. The results indicated that two functional groups, the heterocyclic nitrogen and the amide group, in the nicotinamide or isonicotinamide molecule have a synergistic effect in binding to the polymer. The polymers prepared with nicotinamide and isonicotinamide can be used as HPLC stationary phase for the separation of positional isomers of nicotinamide or isonicotinamide, while the polymer prepared with picolinamide showed no specificity toward the template. The mechanisms for the differences in recognition are discussed, In addition to the retention of polymers to their templates the polymers also displayed excellent retention to nicotinic acid and isonicotinic acid, compounds structurally similar to the template, This dual recognition property of the polymer may be useful in circumstances where the preparation of a polymer for a specific template may be problematic because of poor stability or solubility. Copyright (C) 2001 John Wiley & Sons, Ltd.; Biochemistry & Molecular Biology; Biophysics; SCI(E); PubMed; 25; ARTICLE; 3; 151-156; 14
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/200569]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Fu, Q,Zheng, N,Li, YZ,et al. Molecularly imprinted polymers from nicotinamide and its positional isomers[J]. 分子识别杂志,2001.
APA	Fu, Q,Zheng, N,Li, YZ,Chang, WB,&Wang, ZM.(2001).Molecularly imprinted polymers from nicotinamide and its positional isomers.分子识别杂志.
MLA	Fu, Q,et al."Molecularly imprinted polymers from nicotinamide and its positional isomers".分子识别杂志 (2001).