DL-2-氨基-4-磺酸基-丁酸的溶液结构分析

doi:10.3321/j.issn:1000-0593.2000.05.016

CORC > 北京大学 > 化学与分子工程学院

	DL-2-氨基-4-磺酸基-丁酸的溶液结构分析; The Structure of DL-Homocysteic Acid in D2O Solution
	张煦 ; 杨展澜 ; 李维红 ; 贾会珍 ; 吴瑾光
刊名	光谱学与光谱分析
	2000
关键词	DL-2-氨基-4-磺酸基-丁酸溶液结构 FTIR光谱 DL-homocysteic acid structure in solution FTIR spectroscopy
DOI	10.3321/j.issn:1000-0593.2000.05.016
英文摘要	DL-2-氨基-4-磺酸基-丁酸分子是一种重要的神经传导兴奋性游离氨基酸,本文利用红外光谱、拉曼光谱对其在溶液中的结构进行了分析讨论,结果表明DLH在重水溶液中发生了解离,原来固体分子中的氢键被水分子破坏,重新组合排列形成了新的氢键体系,而且分子的骨架构型也发生了改变.; DL-Homocysteic acid (DLH) is an important free amino acid in central nervous system of human body. In this paper the structure of DLH in D2O solution was discussed. The FTIR and FT-Raman spectra of DLH, which were obained by Nicolet Magna-IR 750 II FTIR spectrometer and 950 FT-Raman spectrometer, were compared between its solid state and its D2O solution. The results indicated that the H-bonding structure of DLH in solid state was rearranged in D2O solution. The appearance of 1 620 and 1 408 cm(-1) suggests the partly ionization of -COOH. From above,we can conclude that a new H-bonding structure of DLH was formed in D2O solution. The H-bond of C-O...H-N was replaced by C-O...D-O,and the H-bonds of -NH3+: and -SO3- were also varied by D2O molecular. Furthermore, the peak shift and the intensity changes of -CH2 in FTIR and FT-Raman spectra were also proved that the skeleton structure of DLH was changed in D2O solution. In addition, this new structure did not alter with the change of concentration of DLH.; 国家高技术研究发展计划(863计划); 科技部科研项目; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000090150100016&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; SCI(E); EI; PubMed; 中文核心期刊要目总览(PKU); 中国科学引文数据库(CSCD); 3; 5; 638-640; 20
语种	中文
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/200213]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	张煦,杨展澜,李维红,等. DL-2-氨基-4-磺酸基-丁酸的溶液结构分析, The Structure of DL-Homocysteic Acid in D2O Solution[J]. 光谱学与光谱分析,2000.
APA	张煦,杨展澜,李维红,贾会珍,&吴瑾光.(2000).DL-2-氨基-4-磺酸基-丁酸的溶液结构分析.光谱学与光谱分析.
MLA	张煦,et al."DL-2-氨基-4-磺酸基-丁酸的溶液结构分析".光谱学与光谱分析 (2000).