Synthesis and photoinduced DNA cleaving activity of hairpin polyamide-chlorobenzenesulfonyl conjugate | |
Tang, FL ; Yuan, G ; Wang, J | |
刊名 | 光化学与光生物学 |
2003 | |
关键词 | MINOR-GROOVE RECOGNITION DESIGN |
DOI | 10.1562/0031-8655(2003)078<0175:SAPDCA>2.0.CO;2 |
英文摘要 | A hairpin polyamide-chlorobenzenesulfonyl conjugate was synthesized in solution by a haloform reaction and the dicyclohexvlcarbodiimide/1-hydroxybenzotriazole (DCC/HOBT) coupling reaction. Its ability to cleave DNA was investigated with supercoiled DNA (pBluescript SK), and the DNA cleaving efficiency of chlorobenzenesulfonyl group was enhanced by the hairpin polyamide under UV irradiation (365 nm).; Biochemistry & Molecular Biology; Biophysics; SCI(E); PubMed; 5; ARTICLE; 2; 175-179; 78 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/200207] |
专题 | 化学与分子工程学院 |
推荐引用方式 GB/T 7714 | Tang, FL,Yuan, G,Wang, J. Synthesis and photoinduced DNA cleaving activity of hairpin polyamide-chlorobenzenesulfonyl conjugate[J]. 光化学与光生物学,2003. |
APA | Tang, FL,Yuan, G,&Wang, J.(2003).Synthesis and photoinduced DNA cleaving activity of hairpin polyamide-chlorobenzenesulfonyl conjugate.光化学与光生物学. |
MLA | Tang, FL,et al."Synthesis and photoinduced DNA cleaving activity of hairpin polyamide-chlorobenzenesulfonyl conjugate".光化学与光生物学 (2003). |
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