Molecularly imprinted polymer using beta-cyclodextrin as functional   monomer for the efficient recognition of bilirubin

doi:10.1016/j.aca.2007.10.044

CORC > 北京大学 > 化学与分子工程学院

	Molecularly imprinted polymer using beta-cyclodextrin as functional monomer for the efficient recognition of bilirubin
	Yang, Yu ; Long, Yuanyuan ; Cao, Qing ; Li, Kean ; Liu, Feng
刊名	analytica chimica acta
	2008
关键词	molecularly imprinted polymer beta-cyclodextrin bilirubin selectivity STATIONARY PHASES ENZYMATIC METHOD HUMAN SERUM OXIDASE CHEMILUMINESCENCE ANTIBODIES SEPARATION TEMPLATES RECEPTORS WATER
DOI	10.1016/j.aca.2007.10.044
英文摘要	Bilirubin (BR) imprinted polymer was successfully prepared using supramolecular host compound P-cyclodextrin (beta-CD) as functional monomer. The adsorption equilibrium was attained in about 4 h, which indicated that the adsorption kinetics was comparatively fast. The results of adsorption and selectivity experiments indicated that BR-imprinted P-CD polymer was able to bind BR specifically and reversibly. The specific recognition of BR-imprinted P-CD polymer for BR may be due to the cooperative effects of inclusion interaction and hydrogen bonding. This BR-imprinted P-CD polymer was further applied to eliminate BR in human serum sample. It was verified that the binding specificity of the BR-imprinted polymer for BR was essentially sufficient in the presence of other compounds coexisting in serum sample. Therefore, as a reusable material possessing high affinity and selectivity, BR-imprinted P-CD polymer has a potential application perspective as a clinical hemoperfusion material. (c) 2007 Elsevier B.V. All rights reserved.; Chemistry, Analytical; SCI(E); PubMed; 52; ARTICLE; 1; 92-97; 606
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/197820]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Yang, Yu,Long, Yuanyuan,Cao, Qing,et al. Molecularly imprinted polymer using beta-cyclodextrin as functional monomer for the efficient recognition of bilirubin[J]. analytica chimica acta,2008.
APA	Yang, Yu,Long, Yuanyuan,Cao, Qing,Li, Kean,&Liu, Feng.(2008).Molecularly imprinted polymer using beta-cyclodextrin as functional monomer for the efficient recognition of bilirubin.analytica chimica acta.
MLA	Yang, Yu,et al."Molecularly imprinted polymer using beta-cyclodextrin as functional monomer for the efficient recognition of bilirubin".analytica chimica acta (2008).