Molecularly imprinted polymer using beta-cyclodextrin as functional monomer for the efficient recognition of bilirubin | |
Yang, Yu ; Long, Yuanyuan ; Cao, Qing ; Li, Kean ; Liu, Feng | |
刊名 | analytica chimica acta
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2008 | |
关键词 | molecularly imprinted polymer beta-cyclodextrin bilirubin selectivity STATIONARY PHASES ENZYMATIC METHOD HUMAN SERUM OXIDASE CHEMILUMINESCENCE ANTIBODIES SEPARATION TEMPLATES RECEPTORS WATER |
DOI | 10.1016/j.aca.2007.10.044 |
英文摘要 | Bilirubin (BR) imprinted polymer was successfully prepared using supramolecular host compound P-cyclodextrin (beta-CD) as functional monomer. The adsorption equilibrium was attained in about 4 h, which indicated that the adsorption kinetics was comparatively fast. The results of adsorption and selectivity experiments indicated that BR-imprinted P-CD polymer was able to bind BR specifically and reversibly. The specific recognition of BR-imprinted P-CD polymer for BR may be due to the cooperative effects of inclusion interaction and hydrogen bonding. This BR-imprinted P-CD polymer was further applied to eliminate BR in human serum sample. It was verified that the binding specificity of the BR-imprinted polymer for BR was essentially sufficient in the presence of other compounds coexisting in serum sample. Therefore, as a reusable material possessing high affinity and selectivity, BR-imprinted P-CD polymer has a potential application perspective as a clinical hemoperfusion material. (c) 2007 Elsevier B.V. All rights reserved.; Chemistry, Analytical; SCI(E); PubMed; 52; ARTICLE; 1; 92-97; 606 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/197820] ![]() |
专题 | 化学与分子工程学院 |
推荐引用方式 GB/T 7714 | Yang, Yu,Long, Yuanyuan,Cao, Qing,et al. Molecularly imprinted polymer using beta-cyclodextrin as functional monomer for the efficient recognition of bilirubin[J]. analytica chimica acta,2008. |
APA | Yang, Yu,Long, Yuanyuan,Cao, Qing,Li, Kean,&Liu, Feng.(2008).Molecularly imprinted polymer using beta-cyclodextrin as functional monomer for the efficient recognition of bilirubin.analytica chimica acta. |
MLA | Yang, Yu,et al."Molecularly imprinted polymer using beta-cyclodextrin as functional monomer for the efficient recognition of bilirubin".analytica chimica acta (2008). |
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