Systems Biology Brings New Dimensions for Structure-Based Drug Design | |
Pei, Jianfeng ; Yin, Ning ; Ma, Xiaomin ; Lai, Luhua | |
刊名 | journal of the american chemical society
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2014 | |
关键词 | PROTEIN-PROTEIN INTERACTIONS SMALL-MOLECULE INHIBITORS DE-NOVO DESIGN TRADITIONAL CHINESE MEDICINE ACID METABOLIC NETWORK OF-THE-ART BINDING-SITES COMPUTATIONAL METHODS COMBINATION THERAPY ANTICANCER STRATEGY |
DOI | 10.1021/ja504810z |
英文摘要 | In this Perspective, we focus on new, systems-centric views of structure-based drug design (SBDD) that we believe will impact future drug discovery research and development. We will first discuss new ways to identify drug targets based on systems intervention analysis, and then we will introduce emerging SBDD methods driven by advancements in systems biology.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000340737900001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Multidisciplinary; SCI(E); EI; PubMed; 12; ARTICLE; lhlai@pku.edu.cn; 33; 11556-11565; 136 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/164072] ![]() |
专题 | 化学与分子工程学院 生命科学学院 |
推荐引用方式 GB/T 7714 | Pei, Jianfeng,Yin, Ning,Ma, Xiaomin,et al. Systems Biology Brings New Dimensions for Structure-Based Drug Design[J]. journal of the american chemical society,2014. |
APA | Pei, Jianfeng,Yin, Ning,Ma, Xiaomin,&Lai, Luhua.(2014).Systems Biology Brings New Dimensions for Structure-Based Drug Design.journal of the american chemical society. |
MLA | Pei, Jianfeng,et al."Systems Biology Brings New Dimensions for Structure-Based Drug Design".journal of the american chemical society (2014). |
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