Systems Biology Brings New Dimensions for Structure-Based Drug Design

doi:10.1021/ja504810z

CORC > 北京大学 > 化学与分子工程学院

	Systems Biology Brings New Dimensions for Structure-Based Drug Design
	Pei, Jianfeng ; Yin, Ning ; Ma, Xiaomin ; Lai, Luhua
刊名	journal of the american chemical society
	2014
关键词	PROTEIN-PROTEIN INTERACTIONS SMALL-MOLECULE INHIBITORS DE-NOVO DESIGN TRADITIONAL CHINESE MEDICINE ACID METABOLIC NETWORK OF-THE-ART BINDING-SITES COMPUTATIONAL METHODS COMBINATION THERAPY ANTICANCER STRATEGY
DOI	10.1021/ja504810z
英文摘要	In this Perspective, we focus on new, systems-centric views of structure-based drug design (SBDD) that we believe will impact future drug discovery research and development. We will first discuss new ways to identify drug targets based on systems intervention analysis, and then we will introduce emerging SBDD methods driven by advancements in systems biology.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000340737900001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Multidisciplinary; SCI(E); EI; PubMed; 12; ARTICLE; lhlai@pku.edu.cn; 33; 11556-11565; 136
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/164072]
专题	化学与分子工程学院生命科学学院
推荐引用方式 GB/T 7714	Pei, Jianfeng,Yin, Ning,Ma, Xiaomin,et al. Systems Biology Brings New Dimensions for Structure-Based Drug Design[J]. journal of the american chemical society,2014.
APA	Pei, Jianfeng,Yin, Ning,Ma, Xiaomin,&Lai, Luhua.(2014).Systems Biology Brings New Dimensions for Structure-Based Drug Design.journal of the american chemical society.
MLA	Pei, Jianfeng,et al."Systems Biology Brings New Dimensions for Structure-Based Drug Design".journal of the american chemical society (2014).