Site-Specific Engineering of Chemical Functionalities on the Surface of   Live Hepatitis D Virus

doi:10.1002/anie.201305787

CORC > 北京大学 > 化学与分子工程学院

	Site-Specific Engineering of Chemical Functionalities on the Surface of Live Hepatitis D Virus
	Lin, Shixian ; Yan, Huan ; Li, Lin ; Yang, Maiyun ; Peng, Bo ; Chen, She ; Li, Wenhui ; Chen, Peng R.
刊名	angewandte chemie international edition
	2013
关键词	click chemistry hepatitisD virus site-specific engineering unnatural amino acids B-VIRUS GENETIC-CODE DELTA VIRUS MAMMALIAN-CELLS PROTEINS PARTICLES INFECTION DISEASE DOMAIN ENTRY
DOI	10.1002/anie.201305787
英文摘要	Precise virus labeling: The genetic code expansion strategy was coupled with an engineered virus assembly process in human hepatocytes to produce intact human hepatitis D virus (HDV) bearing a genetically encoded unnatural amino acid. The resultant HDV virions, with one type of five different pyrrolysine analogues introduced site-specifically into virus surface proteins, exhibited near wild-type viability and infectivity. Copyright ? 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.; Chemistry, Multidisciplinary; SCI(E); EI; 0; ARTICLE; 52; 13970-13974; 52
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/150692]
专题	化学与分子工程学院生命科学学院
推荐引用方式 GB/T 7714	Lin, Shixian,Yan, Huan,Li, Lin,et al. Site-Specific Engineering of Chemical Functionalities on the Surface of Live Hepatitis D Virus[J]. angewandte chemie international edition,2013.
APA	Lin, Shixian.,Yan, Huan.,Li, Lin.,Yang, Maiyun.,Peng, Bo.,...&Chen, Peng R..(2013).Site-Specific Engineering of Chemical Functionalities on the Surface of Live Hepatitis D Virus.angewandte chemie international edition.
MLA	Lin, Shixian,et al."Site-Specific Engineering of Chemical Functionalities on the Surface of Live Hepatitis D Virus".angewandte chemie international edition (2013).