A DNA-templated synthesis of encoded small molecules by DNA   self-assembly

CORC > 北京大学 > 化学与分子工程学院

	A DNA-templated synthesis of encoded small molecules by DNA self-assembly
	Cao, Cheng ; Zhao, Peng ; Li, Ze ; Chen, Zitian ; Huang, Yanyi ; Bai, Yu ; Li, Xiaoyu
刊名	chemical communications
	2014
关键词	IN-VITRO SELECTION CHEMICAL LIBRARIES COMBINATORIAL CHEMISTRY ORGANIC-SYNTHESIS INHIBITORS DISCOVERY MACROCYCLES TRANSLATION INFLUENZA DESIGN
DOI	10.1039/c4cc03380a
英文摘要	We report a novel method for the synthesis of DNA-encoded libraries without the need for discrete DNA template. Reactant DNAs self-assemble to enable chemical reactions and photo-cleavage transfers the product to the DNA terminus, making it suitable for the subsequent affinity-based selection and hit deconvolution.; Chemistry, Multidisciplinary; SCI(E); 2; ARTICLE; yu.bai@pku.edu.cn; xiaoyuli@pku.edu.cn; 75; 10997-10999; 50
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/150644]
专题	化学与分子工程学院工学院
推荐引用方式 GB/T 7714	Cao, Cheng,Zhao, Peng,Li, Ze,et al. A DNA-templated synthesis of encoded small molecules by DNA self-assembly[J]. chemical communications,2014.
APA	Cao, Cheng.,Zhao, Peng.,Li, Ze.,Chen, Zitian.,Huang, Yanyi.,...&Li, Xiaoyu.(2014).A DNA-templated synthesis of encoded small molecules by DNA self-assembly.chemical communications.
MLA	Cao, Cheng,et al."A DNA-templated synthesis of encoded small molecules by DNA self-assembly".chemical communications (2014).