Electron impact mass spectral fragmentation of 2a,4-disubstituted   2-chloro/2,2-dichloro-2,2a,3,4-tetrahydro-1H-azeto[2,   1-d][1,5]benzothiazepin-1-ones

doi:10.1002/(SICI)1097-0231(20000430)14:8&lt;637::AID-RCM924&gt;3.0.CO;2-B

CORC > 北京大学 > 化学与分子工程学院

	Electron impact mass spectral fragmentation of 2a,4-disubstituted 2-chloro/2,2-dichloro-2,2a,3,4-tetrahydro-1H-azeto[2, 1-d][1,5]benzothiazepin-1-ones
	Xu, JX ; Jiao, P ; Zuo, G ; Jin, S
刊名	质谱学快讯
	2000
DOI	10.1002/(SICI)1097-0231(20000430)14:8<637::AID-RCM924>3.0.CO;2-B
英文摘要	The mass spectrometric behaviour of nine 2a,4-disubstituted 2-chloro/2,2-dichloro-2,2a,3,4-tetrahydro azeto[2,1-d][1,5]benzothiazepin-1-ones has been studied with the aid of mass-analysed ion kinetic energy, spectrometry and accurate mass measurements under electron impact ionization. All compounds show a tendency to eliminate a neutral chlorine atom, or a chloroketene, or neutral propene, or styrene or substituted styrene molecule, plus Cl and/or H (or Cl) atom(s), to yield [M - Cl](+) ions, 2,3-dihydro-1,5-benzothiazepine derivative ions, 4,5-dihydro-5H-1,5-benzothiazepin-4-one ions which can further lose CO to give 1,4-benzothiazine ions, Both molecular ions and [M - Cl](+) ions show a tendency to eliminate an ethyl or benzyl/substituted benzyl radical to produce 2,2a-dihydro-1H-azeto[2,1-c][1,4]benzothiazin-1-one ions. The [M - Cl](+) ions could undergo rearrangement to yield 2,2a-dihydro-1H-azeto[2,1-d][1,5]benzothiaze-pin-1-one ions, 2,2a,3,4-tetrahydro-1H-azeto[1,2-a]quinoline ions or 1,1a,2,3-tetrahydro-azirino[2,1-d][1,5]benzothiazepine ions by loss of an ethane or a benzene/substituted benzene, a SH radical or a CO molecule. The molecular ions could also undergo rearrangement reactions to form other small fragment ions. Copyright (C) 2000 John Wiley & Sons, Ltd.; Chemistry, Analytical; Spectroscopy; SCI(E); PubMed; 9; ARTICLE; 8; 637-640; 14
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/150291]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Xu, JX,Jiao, P,Zuo, G,et al. Electron impact mass spectral fragmentation of 2a,4-disubstituted 2-chloro/2,2-dichloro-2,2a,3,4-tetrahydro-1H-azeto[2, 1-d][1,5]benzothiazepin-1-ones[J]. 质谱学快讯,2000.
APA	Xu, JX,Jiao, P,Zuo, G,&Jin, S.(2000).Electron impact mass spectral fragmentation of 2a,4-disubstituted 2-chloro/2,2-dichloro-2,2a,3,4-tetrahydro-1H-azeto[2, 1-d][1,5]benzothiazepin-1-ones.质谱学快讯.
MLA	Xu, JX,et al."Electron impact mass spectral fragmentation of 2a,4-disubstituted 2-chloro/2,2-dichloro-2,2a,3,4-tetrahydro-1H-azeto[2, 1-d][1,5]benzothiazepin-1-ones".质谱学快讯 (2000).