An i-DNA based electrochemical sensor for proton detection

doi:10.1016/j.talanta.2010.06.019

CORC > 北京大学 > 化学与分子工程学院

	An i-DNA based electrochemical sensor for proton detection
	Xu, Xiaodong ; Li, Bo ; Xie, Xiang ; Li, Xiaohui ; Shen, Li ; Shao, Yuanhua
刊名	talanta
	2010
关键词	i-DNA i-Motif Conformation change Electrochemical proton sensor CONFORMATIONAL SWITCH CHEMICAL OSCILLATOR MOLECULAR BEACONS DRIVEN THROMBIN MOTIF QUADRUPLEXES APTASENSOR SEQUENCES APTAMERS
DOI	10.1016/j.talanta.2010.06.019
英文摘要	An i-DNA based electrochemical proton sensor which is fabricated by attaching the ferrocene-labeled i-DNA (Fc-i-DNA) onto a gold electrode is reported. This type of i-DNA is a cytidine-rich single-stranded oligonucleotide that its conformation can be switched between the random coil conformation and the folded i-motif structure at different pH values. The fc-i-DNA is thiol terminated and can be bound to the gold electrode surface by Au-S interaction. With the variation of solution pH, the distance between ferrocene moiety and electrode surface is changed, leading to different redox currents. The pH can then be determined by measurement of the corresponding currents. In the range of pH 5.6-7.1, it is shown a linear relationship between the currents and pH values. The proton sensor also exhibits quick response, easy fabrication, and good selectivity. (C) 2010 Elsevier B.V. All rights reserved.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282480500006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Analytical; SCI(E); EI; PubMed; 7; ARTICLE; 4; 1122-1125; 82
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/150007]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Xu, Xiaodong,Li, Bo,Xie, Xiang,et al. An i-DNA based electrochemical sensor for proton detection[J]. talanta,2010.
APA	Xu, Xiaodong,Li, Bo,Xie, Xiang,Li, Xiaohui,Shen, Li,&Shao, Yuanhua.(2010).An i-DNA based electrochemical sensor for proton detection.talanta.
MLA	Xu, Xiaodong,et al."An i-DNA based electrochemical sensor for proton detection".talanta (2010).