Cell-selective metabolic labeling of biomolecules with bioorthogonal   functionalities

doi:10.1016/j.cbpa.2013.07.006

CORC > 北京大学 > 化学与分子工程学院

	Cell-selective metabolic labeling of biomolecules with bioorthogonal functionalities
	Xie, Ran ; Hong, Senlian ; Chen, Xing
刊名	化学生物学新见
	2013
关键词	GLCNAC-MODIFIED PROTEINS TRANSFER-RNA SYNTHETASE IN-VIVO CHEMICAL REPORTERS CLICK CHEMISTRY LIVE CELLS GLYCANS ZEBRAFISH LIPOSOMES DELIVERY
DOI	10.1016/j.cbpa.2013.07.006
英文摘要	Metabolic labeling of biomolecules with bioorthogonal functionalities enables visualization, enrichment, and analysis of the biomolecules of interest in their physiological environments. This versatile strategy has found utility in probing various classes of biomolecules in a broad range of biological processes. On the other hand, metabolic labeling is nonselective with respect to cell type, which imposes limitations for studies performed in complex biological systems. Herein, we review the recent methodological developments aiming to endow metabolic labeling strategies with cell-type selectivity. The cell-selective metabolic labeling strategies have emerged from protein and glycan labeling. We envision that these strategies can be readily extended to labeling of other classes of biomolecules.; Biochemistry & Molecular Biology; Biophysics; SCI(E); PubMed; 4; REVIEW; 5; 747-752; 17
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/149780]
专题	化学与分子工程学院生命科学学院
推荐引用方式 GB/T 7714	Xie, Ran,Hong, Senlian,Chen, Xing. Cell-selective metabolic labeling of biomolecules with bioorthogonal functionalities[J]. 化学生物学新见,2013.
APA	Xie, Ran,Hong, Senlian,&Chen, Xing.(2013).Cell-selective metabolic labeling of biomolecules with bioorthogonal functionalities.化学生物学新见.
MLA	Xie, Ran,et al."Cell-selective metabolic labeling of biomolecules with bioorthogonal functionalities".化学生物学新见 (2013).