QQ客服 官方微博 反馈留言

	黄连与甘草化学成分的相互作用研究之一——混浊汤剂中沉淀部分的成分研究; Study on the interactions between rhizoma coptidis and radix glycyrrhiza
	李赛君 ; 王凡 ; 赵晶晶 ; 陈惠 ; 吴瑾光
	2007
关键词	黄连 甘草 HPLC TOP-MS FTIR rhizoma coptidis radix glycyrrhiza HPLC FTIR TOF-MS
英文摘要	以黄连与甘草为配伍组成的复方是一种沉淀性配伍,它属于仲景古方系列之一。其汤剂呈混浊状,分别对离心分离后的溶液与沉淀物的成分进行研究。运用高效液相色谱(HPLC)、傅里叶变换红外光谱(FTIR)和飞行时间质谱(TOF-MS)的方法,对单煎黄连、单煎甘草和混煎黄连与甘草的溶液和沉淀物的结构组成进行研究。文章着重报道沉淀物成分的研究,同时还将混煎沉淀物和溶液的谱学行为做了比较。结果发现,在混煎黄连与甘草的沉淀物中,黄连的有些化学成分被保留下来,有些成分却被抑制了;而甘草的化学成分基本都消失了;同时在混煎黄连与甘草的沉淀物中还产生了在单煎黄连与单煎甘草中所没有的一些新物质。此结果说明黄连与甘草在混煎后...; Ancient prescription rhiaoma coptidis powder is a kind of traditional Chinese medicine compounds (TCMC) which is composed of rhizoma coptidis (RC) and radix glycyrrhiza (RG). In the present investigation, the compositions in solutions and precipitates of single decocted RC and RG, and decocted RC-RG mixture were studied by FTIR spectroscopy, HPLC technique and TOF-MS method. The components of decocted RC-RG mixture are different from those of the addition of RC and RG, suggesting that the interactions between RC and RG occurred. The results of FTIR spectroscopic characterization, and HPLC and TOF-MS measurements demonstrated that in both solutions and precipitates some new chemical compounds formed, while some components in the original single decocted RC and RG were restrained in the mixed system, indicating that RG plays an important role in this TCMC-rhizoma coptidis powder.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000246217100026&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; SCI(E); EI; PubMed; 中文核心期刊要目总览(PKU); 中国科技核心期刊(ISTIC); 中国科学引文数据库(CSCD); 1; 04; 730-734; 27
语种	中文
出处	PubMed ; SCI ; 万方 ; 知网
出版者	光谱学与光谱分析
内容类型	其他
源URL	[http://hdl.handle.net/20.500.11897/77914]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	李赛君,王凡,赵晶晶,等. 黄连与甘草化学成分的相互作用研究之一——混浊汤剂中沉淀部分的成分研究, Study on the interactions between rhizoma coptidis and radix glycyrrhiza. 2007-01-01.

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。