Enzymatic Degradation of Supramolecular Materials Based on Partial Inclusion Complex Formation between alpha-Cyclodextrin and Poly(epsilon-caprolactone)

	Enzymatic Degradation of Supramolecular Materials Based on Partial Inclusion Complex Formation between alpha-Cyclodextrin and Poly(epsilon-caprolactone)
	Luo, Haiya ; Meng, Xianwei ; Cheng, Cong ; Dong, Zhenqiang ; Zhang, Sheng ; Li, Bangjing
刊名	JOURNAL OF PHYSICAL CHEMISTRY B
	2010
卷号	114 期号:13 页码:4739-4745
ISSN号	1520-6106
通讯作者	Zhang, S, Sichuan Univ, Polymer Res Inst, State Key Lab Polymer Mat Engn, Chengdu 610065, Peoples R China
产权排序	2
中文摘要	Supramolecular biomaterials were prepared based on the formation of partial inclusion complexes between alpha-CD and poly(epsilon-caprolactone) (PCL). Enzyme-catalyzed degradation of these partial alpha-CD -PCL inclusion complexes was investigated at 37 degrees C in the presence of lipase from pancreas porcine. The biodegradation behaviors were monitored by weight loss measurement, H-1 NMR, XRD, GPC, DSC, and SEM. It was found that the formation of inclusion segments significantly accelerated the degradation of materials. A mechanism of enzymatic degradation for partial alpha-CD-PCL inclusion complexes was proposed. The present study provides a preliminary understanding for the biodegradation of the materials constructed by self-assembly between cyclodextrin and polymers.
学科主题	Chemistry, Physical
收录类别	SCI
资助信息	National Natural Science Foundation of China [50703025, 30600148]
语种	英语
WOS记录号	WOS:000276096600042
公开日期	2011-07-08
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/18389]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Luo, Haiya,Meng, Xianwei,Cheng, Cong,et al. Enzymatic Degradation of Supramolecular Materials Based on Partial Inclusion Complex Formation between alpha-Cyclodextrin and Poly(epsilon-caprolactone)[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2010,114(13):4739-4745.
APA	Luo, Haiya,Meng, Xianwei,Cheng, Cong,Dong, Zhenqiang,Zhang, Sheng,&Li, Bangjing.(2010).Enzymatic Degradation of Supramolecular Materials Based on Partial Inclusion Complex Formation between alpha-Cyclodextrin and Poly(epsilon-caprolactone).JOURNAL OF PHYSICAL CHEMISTRY B,114(13),4739-4745.
MLA	Luo, Haiya,et al."Enzymatic Degradation of Supramolecular Materials Based on Partial Inclusion Complex Formation between alpha-Cyclodextrin and Poly(epsilon-caprolactone)".JOURNAL OF PHYSICAL CHEMISTRY B 114.13(2010):4739-4745.