Binding Mode between Trp-Dy(III) Complex and Herring Sperm DNA

	Binding Mode between Trp-Dy(III) Complex and Herring Sperm DNA
	Zhao, N ; Wang, XM ; Wang, D ; Xu, Y ; Pan, HZ ; Ding, LS
刊名	CHINESE JOURNAL OF INORGANIC CHEMISTRY
	2009
卷号	25 期号:12 页码:2129_2136
关键词	tryptophan Dy(III) herring sperm DNA binding mode
ISSN号	1001-4861
通讯作者	Wang, XM, SW Univ Sci & Technol, Dept Chem, Sch Mat Sci & Engn, Mianyang 621010, Sichuan, Taiwan.
产权排序	2
中文摘要	By means of UV and fluorescence spectra, the binding ratios between Dy(III)(Trp)(3) and DNA. in physiological pH environment(pH7.40) were determined as n(Dy(III)(Trp)),:n(DNA) = 2:1 and n(Dy(III)):n(Trp)=1:3. The binding constant of K-25 degrees C= 5.75 x 10(7) L.mol(-1) and K-37 degrees C=3.27 x 10(5) L.mol(-1) were obtained by double reciprocal method. Thermodynamic function computation demonstrates that Delta S-r(m)circle minus and Delta H-r(m)circle minus are the primary driving power of the interaction between Dy(III)(Trp)(3) and DNA. By combination analysis of the Scatchard and viscometry methods, we suggested that the interaction mode between Dy(III)(Trp)(3) complex and herring sperm DNA be electrostatic and intercalation bindings.
学科主题	Chemistry, Inorganic & Nuclear
收录类别	SCI
语种	中文
WOS记录号	WOS:000273412300010
公开日期	2011-07-08
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/18219]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Zhao, N,Wang, XM,Wang, D,et al. Binding Mode between Trp-Dy(III) Complex and Herring Sperm DNA[J]. CHINESE JOURNAL OF INORGANIC CHEMISTRY,2009,25(12):2129_2136.
APA	Zhao, N,Wang, XM,Wang, D,Xu, Y,Pan, HZ,&Ding, LS.(2009).Binding Mode between Trp-Dy(III) Complex and Herring Sperm DNA.CHINESE JOURNAL OF INORGANIC CHEMISTRY,25(12),2129_2136.
MLA	Zhao, N,et al."Binding Mode between Trp-Dy(III) Complex and Herring Sperm DNA".CHINESE JOURNAL OF INORGANIC CHEMISTRY 25.12(2009):2129_2136.