Arsenic methylation and skin lesions in migrant and native adult women with chronic exposure to arsenic from drinking groundwater

doi:10.1007/s10653-016-9809-1

	Arsenic methylation and skin lesions in migrant and native adult women with chronic exposure to arsenic from drinking groundwater
	Wei, Binggan 1; Yu, Jiangping 1; Yang, Linsheng 1; Li, Hairong 1; Chai, Yuanqing 1,3; Xia, Yajuan 2; Wu, Kegong 2; Gao, Jianwei 1,2; Guo, Zhiwei ; Cui, Na 2
刊名	ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
	2017-02-01
卷号	39 期号:1 页码:89-98
关键词	Arsenic Skin lesion methylation capacity Drinking water Adult women
ISSN号	0269-4042
DOI	10.1007/s10653-016-9809-1
通讯作者	Yang, Linsheng(yangls@igsnrr.ac.cn)
英文摘要	In order to figure out the prevalence of skin lesions and methylation capacity for migrant and native adult women in an endemic area for arsenic poisoning in Inner Mongolia, China, 207 adult women were selected for study subjects. The results showed that the prevalence of skin lesions for the external group, provincial group and native group was 36.54, 26.15 and 35.56 %, respectively. The nail content of arsenic and urinary concentrations of dimethylarsenic (DMA), monomethylarsenic (MMA) and inorganic arsenic (iAs) were significantly higher in women with skin lesions than in those without skin lesions. The highest urinary concentrations of DMA, MMA and iAs were 213.93, 45.72 and 45.01 mu g/L in the native group. The arsenic methylation capacity index revealed that the external group had the greatest capacity, while the native group had the lowest. The odds ratios of skin lesions in relation to arsenic metabolites and arsenic methylation capacity varied widely among the three groups. Urinary MMA and iAs concentrations were positively associated with risk of skin lesions in the three groups of adult women, while primary and secondary methylation capacities were negatively related to risk of skin lesions in native and provincial groups. The external group might be more susceptible to MMA and iAs, while the provincial and native groups were more tolerance to MMA and iAs. Lower primary and secondary arsenic methylation capacities increased the risk of skin lesions in native and provincial groups. Moreover, higher nail arsenic concentration increased the risk of skin lesions of adult women.
资助项目	State Key Program of National Natural Science of China[41230749] ; National Public Welfare sectors (Agriculture) special research Project[201203012-6]
WOS关键词	INNER-MONGOLIA ; SOUTHWESTERN TAIWAN ; HYPERENDEMIC AREAS ; NORTHERN CHINA ; HETAO PLAIN ; WATER ; BANGLADESH ; METABOLISM ; RISK ; POPULATION
WOS研究方向	Engineering ; Environmental Sciences & Ecology ; Public, Environmental & Occupational Health ; Water Resources
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000396347100007
资助机构	State Key Program of National Natural Science of China ; National Public Welfare sectors (Agriculture) special research Project
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/64789]
专题	中国科学院地理科学与资源研究所
通讯作者	Yang, Linsheng
作者单位	1.Chinese Acad Sci, Key Lab Land Surface Pattern & Simulat, Inst Geog Sci & Nat Resources Res, 11 A Datun Rd, Beijing 100101, Peoples R China 2.Inner Mongolia Ctr Endem Dis Control & Res, Hohhot, Inner Mongolia, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Wei, Binggan,Yu, Jiangping,Yang, Linsheng,et al. Arsenic methylation and skin lesions in migrant and native adult women with chronic exposure to arsenic from drinking groundwater[J]. ENVIRONMENTAL GEOCHEMISTRY AND HEALTH,2017,39(1):89-98.
APA	Wei, Binggan.,Yu, Jiangping.,Yang, Linsheng.,Li, Hairong.,Chai, Yuanqing.,...&Cui, Na.(2017).Arsenic methylation and skin lesions in migrant and native adult women with chronic exposure to arsenic from drinking groundwater.ENVIRONMENTAL GEOCHEMISTRY AND HEALTH,39(1),89-98.
MLA	Wei, Binggan,et al."Arsenic methylation and skin lesions in migrant and native adult women with chronic exposure to arsenic from drinking groundwater".ENVIRONMENTAL GEOCHEMISTRY AND HEALTH 39.1(2017):89-98.