Effect modification of the association between temperature variability and daily cardiovascular mortality by air pollutants in three Chinese cities

doi:10.1016/j.envpol.2017.07.045

	Effect modification of the association between temperature variability and daily cardiovascular mortality by air pollutants in three Chinese cities
	Luo, Kai 1,2; Li, Runkui 3; Wang, Zongshuang 4,5; Zhang, Ruiming 1,2; Xu, Qun 1,2
刊名	ENVIRONMENTAL POLLUTION
	2017-11-01
卷号	230 页码:989-999
关键词	Temperature variability Particulate matter Effect modification Cardiovascular mortality China
ISSN号	0269-7491
DOI	10.1016/j.envpol.2017.07.045
通讯作者	Xu, Qun(xuqun@ibms.cams.cn)
英文摘要	There is limited evidence showing the mortality effects of temperature variability (TV) on cardiovascular diseases. The joint effects between TV and air pollutants are also less well-established. This study aims to assess the effect modification of TV-cardiovascular mortality by air pollutants in three Chinese cities (Beijing, Nanjing and Chengdu). Data of daily mortality, air pollutants and meteorological factors from 2008 to 2011 was collected from each city. TV was calculated as the standard deviation of daily maximum and minimum temperatures over exposure days. The city-specific effect estimates of TV on cardiovascular mortality were calculated using a quasi-Poisson regression model, adjusting for potential confounders (e.g., seasonality and temperature). An interaction term of TV and a three-level air pollutants stratum indicator was included in the models. Effect modifications by air pollutants were assessed by comparing the estimates of TV's effect between pollutant stratums and calculating the corresponding 95% confidential interval of the differences. Multivariate meta-analysis was conducted to obtain the pooled estimates. The data showed that TV was associated with increased risk of cardiovascular mortality, especially for longer TV exposure days (0-8 days, TV08). This association was still observed after adjusting for air pollutants on current day or the previous two days. Stronger estimates were observed in females, but no significant difference between males and females was detected, indicating the absence of evidence of effect modification by gender. Estimates of TV-cardiovascular mortality varied across two season periods (warm and cool season) and age groups, but the evidence of effect modification by age and seasons was absent. Regarding the effect modification of TV-cardiovascular mortality association by air pollutants, a significant effect modification was identified for PM10, but not for NO2 and SO2 in the whole population for all TV exposure days. This finding also persisted in subgroups, specifically in females and the elderly. (C) 2017 Elsevier Ltd. All rights reserved.
资助项目	Chinese Ministry of Environmental Protection[200909016] ; China Medical Board[15-230]
WOS关键词	TIME-SERIES ANALYSIS ; PARTICULATE MATTER ; UNITED-STATES ; AMBIENT-TEMPERATURE ; CLIMATE-CHANGE ; HEAT WAVES ; US CITIES ; POLLUTION ; RANGE ; IMPACT
WOS研究方向	Environmental Sciences & Ecology
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000412250900103
资助机构	Chinese Ministry of Environmental Protection ; China Medical Board
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/62300]
专题	中国科学院地理科学与资源研究所
通讯作者	Xu, Qun
作者单位	1.Chinese Acad Med Sci, Peking Union Med Coll, Sch Basic Med, Dept Epidemiol & Biostat,Inst Basic Med Sci, Beijing 100005, Peoples R China 2.Chinese Acad Med Sci, Peking Union Med Coll, Ctr Environm & Hlth Sci, Beijing 100005, Peoples R China 3.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, State Key Lab Resources & Environm Informat Syst, Beijing 100101, Peoples R China 5.Chinese Res Inst Environm Sci, Beijing 100012, Peoples R China
推荐引用方式 GB/T 7714	Luo, Kai,Li, Runkui,Wang, Zongshuang,et al. Effect modification of the association between temperature variability and daily cardiovascular mortality by air pollutants in three Chinese cities[J]. ENVIRONMENTAL POLLUTION,2017,230:989-999.
APA	Luo, Kai,Li, Runkui,Wang, Zongshuang,Zhang, Ruiming,&Xu, Qun.(2017).Effect modification of the association between temperature variability and daily cardiovascular mortality by air pollutants in three Chinese cities.ENVIRONMENTAL POLLUTION,230,989-999.
MLA	Luo, Kai,et al."Effect modification of the association between temperature variability and daily cardiovascular mortality by air pollutants in three Chinese cities".ENVIRONMENTAL POLLUTION 230(2017):989-999.