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	Cyclic Heptapeptides, Cordyheptapeptides C-E, from the Marine-Derived Fungus Acremonium persicinum SCSIO 115 and Their Cytotoxic Activities
	Song, YX; Chen, ZM; Ju, JH; jju@scsio.ac.cn; Zhang, WM; Huang, HB; Chen, YC
刊名	JOURNAL OF NATURAL PRODUCTS
	2012
卷号	75期号:6页码:1215-1219
ISSN号	0163-3864
英文摘要	Three new cycloheptapeptides, cordyheptapeptides C-E (1-3), were isolated from the fermentation extract of the marine-derived fungus Acremonium persicinum SCSIO 115. Their planar structures were elucidated on the basis of extensive MS, as well as 1D and 2D (COSY, HMQC, and HMBC) NMR spectroscopic data analyses. The absolute configurations of the amino acid residues were determined by single-crystal X-ray diffraction, Marfey's method, and chiral-phase HPLC analysis. Compounds 1 and 3 displayed cytotoxicity against SF-268, MCF-7, and NCI-H460 tumor cell lines with IC50 values ranging from 2.5 to 12.1 mu M.
学科主题	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
资助项目	LMB
语种	英语
WOS记录号	WOS:000305503500031
公开日期	2013-08-28
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/9886]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
通讯作者	jju@scsio.ac.cn
推荐引用方式 GB/T 7714	Song, YX,Chen, ZM,Ju, JH,et al. Cyclic Heptapeptides, Cordyheptapeptides C-E, from the Marine-Derived Fungus Acremonium persicinum SCSIO 115 and Their Cytotoxic Activities[J]. JOURNAL OF NATURAL PRODUCTS,2012,75(6):1215-1219.
APA	Song, YX.,Chen, ZM.,Ju, JH.,jju@scsio.ac.cn.,Zhang, WM.,...&Chen, YC.(2012).Cyclic Heptapeptides, Cordyheptapeptides C-E, from the Marine-Derived Fungus Acremonium persicinum SCSIO 115 and Their Cytotoxic Activities.JOURNAL OF NATURAL PRODUCTS,75(6),1215-1219.
MLA	Song, YX,et al."Cyclic Heptapeptides, Cordyheptapeptides C-E, from the Marine-Derived Fungus Acremonium persicinum SCSIO 115 and Their Cytotoxic Activities".JOURNAL OF NATURAL PRODUCTS 75.6(2012):1215-1219.

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