Biotransformation and detoxification of inorganic arsenic in a marine juvenile fish Terapon jarbua after waterborne and dietborne exposure

CORC > 南海海洋研究所 > 中国科学院南海海洋研究所 > 中科院海洋生物资源可持续利用重点实验室

	Biotransformation and detoxification of inorganic arsenic in a marine juvenile fish Terapon jarbua after waterborne and dietborne exposure
	Zhang, W; Huang, LM; Wang, WX; wwang@ust.hk
刊名	JOURNAL OF HAZARDOUS MATERIALS
	2012
卷号	221 页码:162-169
关键词	Arsenic Waterborne Exposure Dietborne Exposure Biotransformation Speciation Fish
ISSN号	0304-3894
英文摘要	Arsenic (As) is a major hazardous metalloid in many aquatic environments. This study quantified the biotransformation of two inorganic As species [As(III) and As(V)] in a marine juvenile grunt Terapon jarbua following waterborne and dietborne exposures for 10 d. The fish were fed As contaminated artificial diets at nominal concentrations of 50,150, and 500 As(III) and As(V)/g (dry weight), and their transformation and growth responses were compared to those exposed to 100 mu g/L waterborne As(III) and As(V). Within the 10 d exposure period, waterborne and dietborne inorganic As exposure had no significant effect on the fish growth performance. The bioaccumulation of As was very low and not proportional to the inorganic As exposure concentration. We demonstrated that both inorganic As(III) and As(V) in the dietborne and waterborne phases were rapidly biotransformed to the less toxic arsenobetaine (AsB, 89-97%). After exposure to inorganic As. T. jarbua developed correspondingly detoxified strategies, such as the reduction of As(V) to As(III) followed by methylation to less toxic organic forms, as well as the synthesis of metal-binding proteins such as metallothionein-like proteins. This study elucidated that As(III) and As(V) had little potential toxicity on marine fish. (C) 2012 Elsevier B.V. All rights reserved.
学科主题	Engineering, Environmental ; Engineering, Civil ; Environmental Sciences
资助项目	LMB
语种	英语
WOS记录号	WOS:000305366000020
公开日期	2013-08-28
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/9878]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
通讯作者	wwang@ust.hk
推荐引用方式 GB/T 7714	Zhang, W,Huang, LM,Wang, WX,et al. Biotransformation and detoxification of inorganic arsenic in a marine juvenile fish Terapon jarbua after waterborne and dietborne exposure[J]. JOURNAL OF HAZARDOUS MATERIALS,2012,221:162-169.
APA	Zhang, W,Huang, LM,Wang, WX,&wwang@ust.hk.(2012).Biotransformation and detoxification of inorganic arsenic in a marine juvenile fish Terapon jarbua after waterborne and dietborne exposure.JOURNAL OF HAZARDOUS MATERIALS,221,162-169.
MLA	Zhang, W,et al."Biotransformation and detoxification of inorganic arsenic in a marine juvenile fish Terapon jarbua after waterborne and dietborne exposure".JOURNAL OF HAZARDOUS MATERIALS 221(2012):162-169.