Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells | |
haoxj@mail.kib.ac.cn; Yang, XW; He, HP; Du, ZZ; Liu, HY; Di, YT; Ma, YL; Wang, F; Lin, H; Zuo, YQ | |
刊名 | CHEMISTRY & BIODIVERSITY
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2009 | |
卷号 | 6期号:4页码:540-550 |
ISSN号 | 1612-1872 |
英文摘要 | Eight new lignan glucosides, tarennanosides A-H (1-8, resp.), were isolated from the whole plant of Tarenna attenuata, together with three known compounds, fernandoside, (-)-lyoniresinol, and (-)isolariciresinol. The planar structures of new compounds were elucidated mainly by analysis of physical and spectroscopic data, and the absolute configurations were determined by acid hydrolysis as well as CD spectroscopy. Compounds I and 2 exhibited potent antioxidant activities against H2O2-induced impairment in PC12 cells. Preliminary mechanism study by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method showed that these two compounds could act as radical scavengers. |
学科主题 | Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary |
URL标识 | 查看原文 |
资助项目 | LMB |
WOS记录号 | WOS:000265475200011 |
公开日期 | 2011-07-03 |
内容类型 | 期刊论文 |
源URL | [http://ir.scsio.ac.cn/handle/344004/5124] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
通讯作者 | haoxj@mail.kib.ac.cn |
推荐引用方式 GB/T 7714 | haoxj@mail.kib.ac.cn,Yang, XW,He, HP,et al. Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells[J]. CHEMISTRY & BIODIVERSITY,2009,6(4):540-550. |
APA | haoxj@mail.kib.ac.cn.,Yang, XW.,He, HP.,Du, ZZ.,Liu, HY.,...&Hao, XJ.(2009).Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells.CHEMISTRY & BIODIVERSITY,6(4),540-550. |
MLA | haoxj@mail.kib.ac.cn,et al."Tarennanosides A-H, Eight New Lignan Glucosides from Tarenna attenuata and Their Protective Effect on H2O2-Induced Impairment in PC12 Cells".CHEMISTRY & BIODIVERSITY 6.4(2009):540-550. |
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