Terpenoid Constituents of Abies chensiensis with Potential Anti-inflammatory Activity

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	Terpenoid Constituents of Abies chensiensis with Potential Anti-inflammatory Activity
	Zeng, HW; Liu, XH; Tang, J; Zhang, WD; wdzhangy@hotmail.com; yangxw76@163.com; Li, YL; Yang, XW; Li, SM; Shen, YH
刊名	JOURNAL OF NATURAL PRODUCTS
	2009
卷号	72 期号:6 页码:1065-1068
ISSN号	0163-3864
英文摘要	Six new triterpenes (neoabieslactones A-F, 1-6) and 17 known compounds were isolated from the aerial parts of Abies chensiensis. The structures of the new triterpenes were proposed by 1D and 2D NMR spectroscopy. Compound 1 was confirmed structurally by X-ray crystallography. In a bioassay against LPS-induced NO production in RAW264.7 macrophages, three compounds, neoabieslactone E (5), (12R,13R)-8,12-epoxy-14-labden-13-ol (7), and manool (8), exhibited IC50 values of 9.1, 1.9, and 9.6 mu g/mL, respectively.
学科主题	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
URL标识	查看原文
资助项目	LMB
WOS记录号	WOS:000267432600015
公开日期	2011-07-03
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/5096]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
通讯作者	wdzhangy@hotmail.com; yangxw76@163.com
推荐引用方式 GB/T 7714	Zeng, HW,Liu, XH,Tang, J,et al. Terpenoid Constituents of Abies chensiensis with Potential Anti-inflammatory Activity[J]. JOURNAL OF NATURAL PRODUCTS,2009,72(6):1065-1068.
APA	Zeng, HW.,Liu, XH.,Tang, J.,Zhang, WD.,wdzhangy@hotmail.com.,...&Shen, YH.(2009).Terpenoid Constituents of Abies chensiensis with Potential Anti-inflammatory Activity.JOURNAL OF NATURAL PRODUCTS,72(6),1065-1068.
MLA	Zeng, HW,et al."Terpenoid Constituents of Abies chensiensis with Potential Anti-inflammatory Activity".JOURNAL OF NATURAL PRODUCTS 72.6(2009):1065-1068.