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	Effects of Al(III) and Nano-Al-13 Species on Malate Dehydrogenase Activity
	Yang, Xiaodi2; Cai, Ling2; Peng, Yu2; Li, Huihui2; Chen, Rong Fu1; Shen, Ren Fang1
刊名	SENSORS
	2011-06-01
卷号	11期号:6页码:5740-5753
关键词	electroanalysis spectroscopy Al(III) Al-13 malate dehydrogenase
ISSN号	1424-8220
DOI	10.3390/s110605740
通讯作者	Shen, Ren Fang(rfshen@issas.ac.cn)
英文摘要	The effects of different aluminum species on malate dehydrogenase (MDH) activity were investigated by monitoring amperometric i-t curves for the oxidation of NADH at low overpotential using a functionalized multi-wall nanotube (MWNT) modified glass carbon electrode (GCE). The results showed that Al(III) and Al-13 can activate the enzymatic activity of MDH, and the activation reaches maximum levels as the Al(III) and Al13 concentration increase. Our study also found that the effects of Al(III) and Al-13 on the activity of MDH depended on the pH value and aluminum speciation. Electrochemical and circular dichroism spectra methods were applied to study the effects of nano-sized aluminum compounds on biomolecules.
收录类别	SCI
WOS关键词	GLUTAMATE-DEHYDROGENASE ; HYDROXYALUMINUM POLYMER ; POLYALUMINUM CHLORIDE ; ALZHEIMERS-DISEASE ; AQUEOUS ALUMINUM ; LANTHANIDE IONS ; AL-13 ; TOXICITY ; WATER ; STABILITY
WOS研究方向	Chemistry ; Electrochemistry ; Instruments & Instrumentation
WOS类目	Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation
语种	英语
出版者	MDPI AG
WOS记录号	WOS:000292026400013
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2558987
专题	南京土壤研究所
通讯作者	Shen, Ren Fang
作者单位	1.Chinese Acad Sci, State Key Lab Soil & Sustainable Agr, Inst Soil Sci, Nanjing 210008, Peoples R China 2.Nanjing Normal Univ, Coll Chem & Mat Sci, Lab Electrochem, Jiangsu Key Lab Biofunct Mat, Nanjing 210097, Peoples R China
推荐引用方式 GB/T 7714	Yang, Xiaodi,Cai, Ling,Peng, Yu,et al. Effects of Al(III) and Nano-Al-13 Species on Malate Dehydrogenase Activity[J]. SENSORS,2011,11(6):5740-5753.
APA	Yang, Xiaodi,Cai, Ling,Peng, Yu,Li, Huihui,Chen, Rong Fu,&Shen, Ren Fang.(2011).Effects of Al(III) and Nano-Al-13 Species on Malate Dehydrogenase Activity.SENSORS,11(6),5740-5753.
MLA	Yang, Xiaodi,et al."Effects of Al(III) and Nano-Al-13 Species on Malate Dehydrogenase Activity".SENSORS 11.6(2011):5740-5753.

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