Imitation of nature: Bionic design in the study of particle adjuvants

doi:10.1016/j.jconrel.2019.04.004

	Imitation of nature: Bionic design in the study of particle adjuvants
	Wu, Jie 1,2; Ma, Guanghui 1,2,3
刊名	JOURNAL OF CONTROLLED RELEASE
	2019-06-10
卷号	303 页码:101-108
关键词	Bionic design Vaccine Adjuvant Nano/micro-particle Pathogen
ISSN号	0168-3659
DOI	10.1016/j.jconrel.2019.04.004
英文摘要	Vaccine adjuvants play an increasingly important role in the development of modern vaccines. Among of them, particle adjuvants have received wide attention due to their unique properties. In order to develop effective particle adjuvants, mimicking natural pathogens is one of the important strategies. By adopting different materials, preparation methods and design ideas, the researchers obtained various particle adjuvants that mimic the shape, surface properties and action mechanisms of natural pathogens. This mini-review outlines some selected relevant recent literatures, discusses several bionic design strategies of particle adjuvants and some important barriers to further study are described.
资助项目	National Natural Science Foundation of China (NSFC)[21576268] ; National Natural Science Foundation of China (NSFC)[21776287] ; National Natural Science Foundation of China (NSFC)[21821005] ; Key Research Program of the Chinese Academy of Sciences[KFZD-SW-218] ; International Cooperation Project of the Chinese Academy of Sciences[122111KYSB20180021]
WOS关键词	DELIVERY-SYSTEM ; BACTERIAL GHOSTS ; VACCINE DELIVERY ; IMMUNE-RESPONSE ; DENDRITIC CELLS ; NANOPARTICLES ; ANTIGEN ; MICROPARTICLES ; SIZE ; ACTIVATION
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000471239600010
资助机构	National Natural Science Foundation of China (NSFC) ; Key Research Program of the Chinese Academy of Sciences ; International Cooperation Project of the Chinese Academy of Sciences
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/30054]
专题	中国科学院过程工程研究所
通讯作者	Ma, Guanghui
作者单位	1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Proc Engn, PLA Key Lab Biopharmaceut Prod & Formulat Engn, Beijing 100190, Peoples R China 3.Jiangsu Natl Synerget Innovat Ctr Adv Mat, Nanjing 211816, Jiangsu, Peoples R China
推荐引用方式 GB/T 7714	Wu, Jie,Ma, Guanghui. Imitation of nature: Bionic design in the study of particle adjuvants[J]. JOURNAL OF CONTROLLED RELEASE,2019,303:101-108.
APA	Wu, Jie,&Ma, Guanghui.(2019).Imitation of nature: Bionic design in the study of particle adjuvants.JOURNAL OF CONTROLLED RELEASE,303,101-108.
MLA	Wu, Jie,et al."Imitation of nature: Bionic design in the study of particle adjuvants".JOURNAL OF CONTROLLED RELEASE 303(2019):101-108.