Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity

doi:10.3390/md16090291

CORC > 海洋研究所 > 中国科学院海洋研究所 > 实验海洋生物学重点实验室

	Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity
	Jin, Weihua 1; Ren, Langlang 1; Liu, Bing 1; Zhang, Quanbin 2,3; Zhong, Weihong 1
刊名	MARINE DRUGS
	2018-09-01
卷号	16 期号:9 页码:12
关键词	glucuronomannan oligosaccharides sulfation antioxidant activity
ISSN号	1660-3397
DOI	10.3390/md16090291
通讯作者	Zhang, Quanbin(qbzhang@qdio.ac.cn) ; Zhong, Weihong(whzhong@zjut.edu.cn)
英文摘要	Glucuronomannan oligosaccharides (Gs) were derived from fucoidan, which was extracted from the brown alga Sargassum thunbergii. Sulfated glucuronomannan oligosaccharides (SGs) were obtained by the sulfation of Gs. NMR techniques were used to reveal that the order of sulfation was Man-C6 > Man-C4 > Man-C1R > GlcA-C3 > Man-C3 > GlcA-C2. Finally, the antioxidant activities (hydroxyl radical scavenging activity, superoxide radical scavenging activity, reducing power and DPPH radical scavenging activity) of Gs and SGs were determined. The findings showed that the higher the degree of polymerization, the better the activity, except for the hydroxyl radical scavenging activity. In addition, the higher the sulfate content, the lower the activities for the reducing power and DPPH radical scavenging activity. Opposite results were found for the superoxide radical scavenging activity. Finally, compared with fucoidan, most Gs and SGs had higher antioxidant activity, suggesting that they might be good candidates for antioxidants.
WOS研究方向	Pharmacology & Pharmacy
语种	英语
出版者	MDPI
WOS记录号	WOS:000445636600002
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/160385]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Zhang, Quanbin; Zhong, Weihong
作者单位	1.Zhejiang Univ Technol, Coll Biotechnol & Bioengn, Hangzhou 310023, Zhejiang, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Lab Expt Marine Biol, Qingdao 266071, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266000, Peoples R China
推荐引用方式 GB/T 7714	Jin, Weihua,Ren, Langlang,Liu, Bing,et al. Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity[J]. MARINE DRUGS,2018,16(9):12.
APA	Jin, Weihua,Ren, Langlang,Liu, Bing,Zhang, Quanbin,&Zhong, Weihong.(2018).Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity.MARINE DRUGS,16(9),12.
MLA	Jin, Weihua,et al."Structural Features of Sulfated Glucuronomannan Oligosaccharides and Their Antioxidant Activity".MARINE DRUGS 16.9(2018):12.