Photoswitchable and WaterSoluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome

doi:10.1002/asia.201601501

	Photoswitchable and WaterSoluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome
	Hu, GF; Fang, SB; Fang, YY; Lin, Y; Hu GF(胡国飞); Cheng HB(程洪波); Cheng, HB; Ma, P; Wang, YN
刊名	CHEMISTRY-AN ASIAN JOURNAL
	2017
卷号	12 期号:2 页码:248-253
关键词	liposomes molecular switch nano-aggregates optical stimuli photochromism
ISSN号	1861-4728
DOI	10.1002/asia.201601501
文献子类	Article
英文摘要	In this work, a unique approach is developed to generate photoswitchable and water-soluble fluorescent nano-aggregates. Initially, a new light-controlled diarylethene-dansyl dyad DAE 1 is formed by linking two dansyl fluorophores covalently to a symmetrical dithienylethene backbone, whose photophysical properties can be reversibly switched by optical stimuli. Subsequently, the water insolubility of the molecular switch 1 is overcome by incorporating it into the bilayer of liposome DPPC (1,2-dihexadecanoyl-sn-glycero-3-phosphocholine) in water. This strategy creates stable fluorescent nano-aggregates OF-1@DPPC (approximate to 25nm diameter) that are soluble in an aqueous medium. The nano-aggregates OF-1@DPPC retain and even improve the photoswitchable fluorescence properties of DAE 1. More importantly, OF-1@DPPC exhibits a remarkable photostability and fatigue resistance after 5 cycles of irradiation with UV and visible light, which is crucial for its practical application.
电子版国际标准刊号	1861-471X
WOS关键词	AMPHIPHILIC SIDE-CHAINS ; UPCONVERTING NANOPARTICLES ; PHOTOCHROMIC DIARYLETHENES ; MOLECULAR SWITCHES ; DERIVATIVES ; ACCEPTORS ; CELLS ; PROBE
WOS研究方向	Chemistry
语种	英语
WOS记录号	WOS:000393434200013
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/284947]
专题	高能物理研究所_多学科研究中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Hu, GF,Fang, SB,Fang, YY,et al. Photoswitchable and WaterSoluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome[J]. CHEMISTRY-AN ASIAN JOURNAL,2017,12(2):248-253.
APA	Hu, GF.,Fang, SB.,Fang, YY.,Lin, Y.,胡国飞.,...&Wang, YN.(2017).Photoswitchable and WaterSoluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome.CHEMISTRY-AN ASIAN JOURNAL,12(2),248-253.
MLA	Hu, GF,et al."Photoswitchable and WaterSoluble Fluorescent Nano-Aggregates Based on a Diarylethene-Dansyl Dyad and Liposome".CHEMISTRY-AN ASIAN JOURNAL 12.2(2017):248-253.