Zika Virus Potentiates the Development of Neurological Defects and Microcephaly: Challenges and Control Strategies

doi:10.3389/fneur.2019.00319

CORC > 水生生物研究所 > 中科院水生所知识产出（2009年前） > 其他

	Zika Virus Potentiates the Development of Neurological Defects and Microcephaly: Challenges and Control Strategies
	Siddique, Rabeea 1,2; Liu, Yang 1,2; Nabi, Ghulam 3,4; Sajjad, Wasim 4,5; Xue, Mengzhou 1,2; Khan, Suliman 1,2,3
刊名	FRONTIERS IN NEUROLOGY
	2019-04-09
卷号	10 页码:9
关键词	Zika virus emerging infection microcephaly neurological disorders public health
ISSN号	1664-2295
DOI	10.3389/fneur.2019.00319
通讯作者	Xue, Mengzhou(xuemengzhou@zzu.edu.cn) ; Khan, Suliman(suliman.khan18@mails.ucas.ac.cn)
英文摘要	Since the beginning of the Zika Virus (ZIKV) epidemic, thousands of cases presenting ZIKV symptoms were recorded in Brazil, Colombia (South America), French Polynesia and other countries of Central and North America. In Brazil, during ZIKV outbreak thousands of microcephaly cases occurred that caused a state of urgency among scientists and researchers to confirm the suspected association between ZIKV infection and microcephaly. In this review article we comprehensively studied scientific literature to analyze ZIKV relationship with microcephaly, recent experimental studies, challenge and shortcomings in previously published reports to know about the current status of this association. The evidences supporting the association of ZIKV infection with congenital microcephaly and fetal brain tissue damage is rapidly increasing, and supplying recent information about pathology, clinical medicine, epidemiology, mechanism and experimental studies. However, serious attention is required toward ZIKV vaccine development, standardization of anthropometric techniques, centralization of data, and advance research to clearly understand the mechanism of ZIKV infection causing microcephaly.
资助项目	National Natural Science Foundation of China[81471174] ; National Natural Science Foundation of China[81520108011] ; National Natural Science Foundation of China[81870942] ; National Key Research and Development Program of China[2018YFC1312200] ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China
WOS关键词	CHRONIC HEPATITIS-B ; INFECTION ; BRAIN ; TRANSMISSION ; PREGNANCY ; BRAZIL ; ASSOCIATION ; EPIDEMIOLOGY ; ENTECAVIR ; ORGANOIDS
WOS研究方向	Neurosciences & Neurology
语种	英语
出版者	FRONTIERS MEDIA SA
WOS记录号	WOS:000463951100001
资助机构	National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; National Key Research and Development Program of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China ; Innovation Scientists and Technicians Troop Constructions Projects of Henan Province of China
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/342005/27799]
专题	水生生物研究所_其他
通讯作者	Xue, Mengzhou; Khan, Suliman
作者单位	1.Zhengzhou Univ, Henan Med Key Lab Translat Cerebrovasc Dis, Zhengzhou, Henan, Peoples R China 2.Zhengzhou Univ, Affiliated Hosp 2, Dept Cerebrovasc Dis, Zhengzhou, Henan, Peoples R China 3.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan, Hubei, Peoples R China 4.Univ Chinese Acad Sci, Beijing, Peoples R China 5.Chinese Acad Sci, Inst Geol & Geophys, Key Lab Petr Resources, Gansu Prov Key Lab Petr Resources Res, Lanzhou, Gansu, Peoples R China
推荐引用方式 GB/T 7714	Siddique, Rabeea,Liu, Yang,Nabi, Ghulam,et al. Zika Virus Potentiates the Development of Neurological Defects and Microcephaly: Challenges and Control Strategies[J]. FRONTIERS IN NEUROLOGY,2019,10:9.
APA	Siddique, Rabeea,Liu, Yang,Nabi, Ghulam,Sajjad, Wasim,Xue, Mengzhou,&Khan, Suliman.(2019).Zika Virus Potentiates the Development of Neurological Defects and Microcephaly: Challenges and Control Strategies.FRONTIERS IN NEUROLOGY,10,9.
MLA	Siddique, Rabeea,et al."Zika Virus Potentiates the Development of Neurological Defects and Microcephaly: Challenges and Control Strategies".FRONTIERS IN NEUROLOGY 10(2019):9.