Preparation approach of monolithic silica column

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	Preparation approach of monolithic silica column
	Gao, WH ; Yang, GL ; Yang, J ; Liu, HY ; Yin, JF ; Chen, Y
刊名	CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
	2004-12-10
卷号	25 期号:12 页码:2250-2252
关键词	Monolithic Silica Column Sol-gel Technology High Performance Liquid Chromatography Pore Structure
ISSN号	0251-0790
英文摘要	A new approach of preparing monolithic silica column was founded by adopting an improved solgel technology with tetramethoxysilane and polyethylene glycol as the matrix materials. The reason of resulting in crack and deformation of monolithic column was explained. By using N,N-dimethylformamide and a heat treatment procedure, the problems of crack and deformation in preparing the column were solved and the drying time was shortened greatly. In addition, the methods of fabricating mesopore and the effects of porogen solvent of different concentrations on monolithic silica column were investigated. The results show that the column prepared possessed bimodal pores structures with micrometer-size co-continuous through-pores and silica skeletons which have nanometer-size mesopores, straight appearance, high porosity, good chemical and mechanical stability. The characteristics would favour the separation with a rapid speed and high efficiency for both small molecules and macromolecules.
语种	英语
出版者	HIGHER EDUCATION PRESS
WOS记录号	WOS:000225904200015
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/82423]
专题	中国科学院化学研究所
通讯作者	Yang, GL
作者单位	1.Hebei Univ, Coll Chem & Environm Sci, Baoding 071002, Peoples R China 2.Hebei Univ Sci & Technol, Coll Biol Sci & Engn, Shijiazhuang 050018, Peoples R China 3.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Gao, WH,Yang, GL,Yang, J,et al. Preparation approach of monolithic silica column[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2004,25(12):2250-2252.
APA	Gao, WH,Yang, GL,Yang, J,Liu, HY,Yin, JF,&Chen, Y.(2004).Preparation approach of monolithic silica column.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,25(12),2250-2252.
MLA	Gao, WH,et al."Preparation approach of monolithic silica column".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 25.12(2004):2250-2252.