A study of residue-residue contacts in globular protein molecules

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	A study of residue-residue contacts in globular protein molecules
	Chen, J ; Li, J ; Zhang, LX ; Jiang, XT ; Xia, AG ; Ye, GX ; Zhao, DL
刊名	ACTA POLYMERICA SINICA
	2003-04-01
期号	2 页码:171-174
关键词	Globular Protein Contact Csu Software Folding
ISSN号	1000-3304
英文摘要	The residue-residue contacts in 61 globular protein molecules were studied by using CSU software. The aim is to find the ability of forming the short-range and long-range residue-residue contacts for several residues. It is found that it is easy to form the long-range residue-residue contacts for Len, Val, Ile, Met, Phe, Tyr, Cys, Trp residues, and it is difficult to form the long-range residue-residue contacts for Glu, Gln, Asp, Asn, Lys, Ser, Arg, Pro residues. The residuce are called residues hydrophobic (H) and hydrophilic (P) residues, respectively, and the other residues is called neutral residue (N). The average number of long-range contacts per residue is 6.03, 4.43 and 3.64 for H, N and P residues respectively. However, the average number of short-range contacts per residue ranges from 2.34 to 2.85, and it is almost no difference among those residues in forming the short-range contacts. Our research may provide some insights into the stability and folding of protein molecules.
语种	英语
出版者	SCIENCE CHINA PRESS
WOS记录号	WOS:000189315400003
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/80781]
专题	中国科学院化学研究所
通讯作者	Chen, J
作者单位	1.Hangzhou Univ, Dept Phys, Hangzhou 310028, Peoples R China 2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Polymer Phys Lab, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Chen, J,Li, J,Zhang, LX,et al. A study of residue-residue contacts in globular protein molecules[J]. ACTA POLYMERICA SINICA,2003(2):171-174.
APA	Chen, J.,Li, J.,Zhang, LX.,Jiang, XT.,Xia, AG.,...&Zhao, DL.(2003).A study of residue-residue contacts in globular protein molecules.ACTA POLYMERICA SINICA(2),171-174.
MLA	Chen, J,et al."A study of residue-residue contacts in globular protein molecules".ACTA POLYMERICA SINICA .2(2003):171-174.