Synthesis and hierarchical structures of amphiphilic polyphenyl acetylenes carrying L-valine pendants

doi:10.1021/ma0213091

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	Synthesis and hierarchical structures of amphiphilic polyphenyl acetylenes carrying L-valine pendants
	Li, BS ; Cheuk, KKL ; Ling, LS ; Chen, JW ; Xiao, XD ; Bai, CL ; Tang, BZ
刊名	MACROMOLECULES
	2003-01-14
卷号	36 期号:1 页码:77-85
ISSN号	0024-9297
DOI	10.1021/ma0213091
英文摘要	In this work, we synthesized amino acid-containing poly(phenylacetylene)s and demonstrated the possibility of tuning their hierarchical structures by internal and external perturbations. A valine-acetylene adduct, 4-ethynylbenzoyl-L-valine methyl ester (5), was readily polymerized by [Rh(nbd)Cl](2), and the resultant "polyester" (1) was selectively hydrolyzed by KOH to its "polyacid" congener, poly(4-ethynylben zoyl-L-valine) (2). (Supra)molecular structures of the polymers were characterized by NMR, IR, UV, CD, and AFM techniques. The macromolecules took helical chain conformations in solutions. Their Cotton effects varied to different extents, when the polymer, solvent, and pH changed respectively from 1 to 2, from methanol to THF, and from neutral to basic. Upon evaporation of their methanol solutions, 1 and 2 self-assembled into micellar spheres and helical cables, respectively. Changing the solvent of 1 to THF changed its folding structure to helical cables, while increasing the pH of the methanol solution of 2 led to the formation of random threads. The denaturation from helical cables to random threads is probably caused by the cleavage of interstrand hydrogen bonds by base-mediated ionization of carboxyl groups of the valine pendants.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000180364900014
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/80429]
专题	中国科学院化学研究所
通讯作者	Bai, CL
作者单位	1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China 2.Hong Kong Univ Sci & Technol, Dept Chem, Inst Nano Sci & Technol, Kowloon, Hong Kong, Peoples R China 3.Hong Kong Univ Sci & Technol, Dept Phys, Inst Nano Sci & Technol, Kowloon, Hong Kong, Peoples R China 4.Hong Kong Univ Sci & Technol, Inst Mol Technol Drug Discovery & Synth, Open Lab Chirotechnol, Kowloon, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Li, BS,Cheuk, KKL,Ling, LS,et al. Synthesis and hierarchical structures of amphiphilic polyphenyl acetylenes carrying L-valine pendants[J]. MACROMOLECULES,2003,36(1):77-85.
APA	Li, BS.,Cheuk, KKL.,Ling, LS.,Chen, JW.,Xiao, XD.,...&Tang, BZ.(2003).Synthesis and hierarchical structures of amphiphilic polyphenyl acetylenes carrying L-valine pendants.MACROMOLECULES,36(1),77-85.
MLA	Li, BS,et al."Synthesis and hierarchical structures of amphiphilic polyphenyl acetylenes carrying L-valine pendants".MACROMOLECULES 36.1(2003):77-85.