Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry studies of low molecular weight dendrimers

doi:10.1255/ejms.547

CORC > 化学研究所 > 中国科学院化学研究所

	Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry studies of low molecular weight dendrimers
	Zhao, ZW; Xiong, SX; Liu, XW; Xin, B; Wang, GH
刊名	EUROPEAN JOURNAL OF MASS SPECTROMETRY
	2003
卷号	9 期号:3 页码:203-211
关键词	Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry Dendrimer Dendrimer Characterization
ISSN号	1469-0667
DOI	10.1255/ejms.547
英文摘要	We report the application of matrix-assisted laser desorption/ionization time-of-flight (MALDI-ToF) mass spectrometry, with delayed extraction in the reflectron mode, for the characterization of low molecular weight dendrimers. 20 dendrimer samples were measured and 4 typical dendrimers, as examples, are discussed in detail. Several factors that affect the analysis including the matrices used, the concentrations of sample, the solvents and cationization reagent used, were investigated in detail. Experimental results indicate that the type of solvent can greatly influence exact mass measurement. However, sample preparation is generally not very critical for dendrimer analysis using MALDI-ToF since many kinds of matrices and a wide range of sample concentrations can be used efficiently. In addition, the Cs+ ion can be used to enhance the efficiency of cationization. Some reasons for this behavior are discussed on the basis of results of calculations using Gaussian94 software (a connected system of programs for performing a variety of semi-empirical and ab initio molecular orbital (MO) calculations).
语种	英语
出版者	IM PUBLICATIONS
WOS记录号	WOS:000185033200006
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/79871]
专题	中国科学院化学研究所
通讯作者	Xiong, SX
作者单位	Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing Mass Spect Ctr, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Zhao, ZW,Xiong, SX,Liu, XW,et al. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry studies of low molecular weight dendrimers[J]. EUROPEAN JOURNAL OF MASS SPECTROMETRY,2003,9(3):203-211.
APA	Zhao, ZW,Xiong, SX,Liu, XW,Xin, B,&Wang, GH.(2003).Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry studies of low molecular weight dendrimers.EUROPEAN JOURNAL OF MASS SPECTROMETRY,9(3),203-211.
MLA	Zhao, ZW,et al."Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry studies of low molecular weight dendrimers".EUROPEAN JOURNAL OF MASS SPECTROMETRY 9.3(2003):203-211.