New potential photodynamic therapeutic anti-cancer agents: synthesis and characterization of demethoxy amino-substituted hypocrellins

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	New potential photodynamic therapeutic anti-cancer agents: synthesis and characterization of demethoxy amino-substituted hypocrellins
	Wu, T; Xu, SJ; Shen, JQ; Song, AM; Chen, S; Zhang, MH; Shen, T
刊名	ANTI-CANCER DRUG DESIGN
	2000-08-01
卷号	15 期号:4 页码:287-293
关键词	Hypocrellin Photodynamic Therapy Photosensitization Singlet Oxygen Superoxide
ISSN号	0266-9536
英文摘要	A novel method was used to obtain demethoxy amino-substituted hypocrellin derivatives. The reaction condition was mild and amino substitution occurred at position 2 or 11 of hypocrellins with high yield. The photophysical and photochemical properties of the amino-substituted hypocrellins derivatives were investigated, and their significantly enhanced red absorptivities and strong active oxygen-generating functions qualified them as promising photodynamic therapeutic anti-cancer agents.
语种	英语
出版者	OXFORD UNIV PRESS
WOS记录号	WOS:000166614600006
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/76075]
专题	中国科学院化学研究所
通讯作者	Wu, T
作者单位	Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Wu, T,Xu, SJ,Shen, JQ,et al. New potential photodynamic therapeutic anti-cancer agents: synthesis and characterization of demethoxy amino-substituted hypocrellins[J]. ANTI-CANCER DRUG DESIGN,2000,15(4):287-293.
APA	Wu, T.,Xu, SJ.,Shen, JQ.,Song, AM.,Chen, S.,...&Shen, T.(2000).New potential photodynamic therapeutic anti-cancer agents: synthesis and characterization of demethoxy amino-substituted hypocrellins.ANTI-CANCER DRUG DESIGN,15(4),287-293.
MLA	Wu, T,et al."New potential photodynamic therapeutic anti-cancer agents: synthesis and characterization of demethoxy amino-substituted hypocrellins".ANTI-CANCER DRUG DESIGN 15.4(2000):287-293.