Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os

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	Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os
	Cheng, Y ; Liu, MZ ; Li, Y ; Li, RC ; Bai, CL ; Wang, K
刊名	CHINESE SCIENCE BULLETIN
	2000-03-01
卷号	45 期号:5 页码:426-429
关键词	Afm Ft-ir Cecl3 Domain Structure Wistar Rat Erythrocyte
ISSN号	1001-6538
英文摘要	To explore the possibility of absorption of lanthanides via digestive duct and their effects on the membrane structure and permeability of erythrocytes, the fine structure of erythrocyte membrane from Wistar rats, fed for 70 days of daily administration per os with 20 mg CeCl3/kg weight, was imaged by means of atomic force microscopy and FT-IR deconvolution spectra. The results show that, although the erythrocytes maintain the intact shape, the change of secondary structure, aggregation and crosslinking of the protein particles of membrane surface and the enlarged lipid regions lead to the domain structure formation. This structure might be responsible for the increasing permeability of erythrocyte membrane.
语种	英语
出版者	SCIENCE PRESS
WOS记录号	WOS:000086025900010
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/75771]
专题	中国科学院化学研究所
通讯作者	Wang, K
作者单位	1.Beijing Med Univ, Nat Res Labs Nat Biomimetr, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Cheng, Y,Liu, MZ,Li, Y,et al. Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os[J]. CHINESE SCIENCE BULLETIN,2000,45(5):426-429.
APA	Cheng, Y,Liu, MZ,Li, Y,Li, RC,Bai, CL,&Wang, K.(2000).Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os.CHINESE SCIENCE BULLETIN,45(5),426-429.
MLA	Cheng, Y,et al."Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os".CHINESE SCIENCE BULLETIN 45.5(2000):426-429.