Synthesis of Amphiphilic Crown Ether Compound and Application in Ion Channel Membrane

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	Synthesis of Amphiphilic Crown Ether Compound and Application in Ion Channel Membrane
	Tang Chengcheng 1,2; Wang Lihua 2,3; Yun Yanbin 1; Zhang Chelin 1; Liu Biqian 2
刊名	ACTA CHIMICA SINICA
	2011-02-14
卷号	69 期号:3 页码:343-350
关键词	Amphiphilic Molecule Self-assembly Ion Channel Membrane Crown Ether Na(+) Recognized
ISSN号	0567-7351
英文摘要	In this research, a kind of amphiphilic compound: 2-hydroxymethyl-[1,4,7,10,13-pentaoxa benzo cyclo pentadecane]-3,4,5-tris[4-(10-dodecyl-l-oxo)benzyloxy]benzoate was synthesized by methyl p-hydroxybenzoate, 4-carbonate benzo-15-crown-5 and other reagents. The chemical composition and structure were characterized by FT-IR, (1)H NMR, MS, DSC and POM. Then, the ion channel membrane was obtained from grafting this new kind of crown ether compound to the surface of polycarbonate track-etched membrane by the method of ultraviolet (UV) light grafting. The grafting volume is: 606 mu g/cm(2). The ion channel membrane was characterized by the method of ATR, SEM and AFM. The results confirmed that the compound had successfully grafted onto the surface of the polycarbonate track-etched membrane, and formed a dense layer by the self-assembly columnar structures. At last, the ion channel function of the membrane was determined by self-designed membrane transport instrument. The ion transport rate: P(FM) = 20.62 X 10(-6)cm/s. The separation factor of ion channel membrane and controlled membrane: alpha(FM/NFM) = 5.96. These data confirmed that the ion channel membrane can selectively recognize and transport Na(+). It is a new type of Na(+) recognized ion channel membrane.
语种	英语
出版者	SCIENCE CHINA PRESS
WOS记录号	WOS:000288184400013
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/73943]
专题	中国科学院化学研究所
通讯作者	Tang Chengcheng
作者单位	1.Beijing Forestry Univ, Coll Environm Sci & Engn, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Inst Chem, New Mat Lab, Beijing 100190, Peoples R China 3.Tianjin Polytechn Univ, State Key Lab Hollow Fiber Membrane Mat & Proc, Tianjin 300160, Peoples R China
推荐引用方式 GB/T 7714	Tang Chengcheng,Wang Lihua,Yun Yanbin,et al. Synthesis of Amphiphilic Crown Ether Compound and Application in Ion Channel Membrane[J]. ACTA CHIMICA SINICA,2011,69(3):343-350.
APA	Tang Chengcheng,Wang Lihua,Yun Yanbin,Zhang Chelin,&Liu Biqian.(2011).Synthesis of Amphiphilic Crown Ether Compound and Application in Ion Channel Membrane.ACTA CHIMICA SINICA,69(3),343-350.
MLA	Tang Chengcheng,et al."Synthesis of Amphiphilic Crown Ether Compound and Application in Ion Channel Membrane".ACTA CHIMICA SINICA 69.3(2011):343-350.