Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior | |
Yan, Shifeng1; Yin, Jingbo1; Tang, Li1; Chen, Xuesi2 | |
刊名 | JOURNAL OF APPLIED POLYMER SCIENCE |
2011-02-15 | |
卷号 | 119期号:4页码:2350-2358 |
关键词 | Hydrogel Crosslinking Carboxymethylchitosan Hydroxyethylcellulose Methylcellulose |
ISSN号 | 0021-8995 |
DOI | 10.1002/app.32678 |
英文摘要 | Novel hydrogels, physically crosslinked by hydrogen bonding of component polymers, were obtained by mixing aqueous solutions of carboxymethylchitosan (CMCS) with cellulose ethers including hydroxyethylcellulose (HEC) and methylcellulose (MC). The hydrogels were characterized by IR, XPS, WAXD, and SEM. The swelling and controlled drug release behaviors of hydrogels were also studied. The results indicate that intermacromolecular hydrogen bonding in CMCS/HEC is stronger than that in CMCS/MC. The swelling and drug release rate of hydrogels decrease as the interaction of component polymers increases. Both the swelling and drug release from hydrogels can be controlled by component polymer ratio. The hydrogels may be potential candidates for biomedical applications. VC 2010 Wiley Periodicals, Inc. J Appl Polym Sci 119: 2350-2358, 2011 |
语种 | 英语 |
出版者 | WILEY-BLACKWELL |
WOS记录号 | WOS:000284233500055 |
内容类型 | 期刊论文 |
源URL | [http://ir.iccas.ac.cn/handle/121111/72109] |
专题 | 中国科学院化学研究所 |
通讯作者 | Yin, Jingbo |
作者单位 | 1.Shanghai Univ, Sch Mat Sci & Engn, Dept Polymer Mat, Shanghai 201800, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China |
推荐引用方式 GB/T 7714 | Yan, Shifeng,Yin, Jingbo,Tang, Li,et al. Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2011,119(4):2350-2358. |
APA | Yan, Shifeng,Yin, Jingbo,Tang, Li,&Chen, Xuesi.(2011).Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior.JOURNAL OF APPLIED POLYMER SCIENCE,119(4),2350-2358. |
MLA | Yan, Shifeng,et al."Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior".JOURNAL OF APPLIED POLYMER SCIENCE 119.4(2011):2350-2358. |
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