PH-responsive nano-assemblies of amino poly(glycerol methacrylate)

doi:10.1016/j.eurpolymj.2011.03.009

CORC > 化学研究所 > 中国科学院化学研究所

	PH-responsive nano-assemblies of amino poly(glycerol methacrylate)
	Gao Hui 1; Ma Yanan 1; Lu Xueyou 1; Liang Yongri 2; Chen Baoquan 1; Ma Jianbiao 1,3
刊名	EUROPEAN POLYMER JOURNAL
	2011-06-01
卷号	47 期号:6 页码:1232-1239
关键词	Ph-sensitive Nanoparticles Amino Polymer Poly(Glycidyl Methacrylate) Congo Red
ISSN号	0014-3057
DOI	10.1016/j.eurpolymj.2011.03.009
英文摘要	Both linear and star-shaped poly(glycidyl methacrylate) (PGMA) polymers were modified with different amines and used to prepare pH-sensitive nano-assemblies. Nanoprecipitation technique and dialysis method were used to prepare the polymeric nanoparticles. These nano-assemblies showed pH-sensitive disassociation properties under an acidic condition. The polymers were quite effective in encapsulation of Congo red (CR). Atom force microscopy images showed that the nanoparticles prepared using nanoprecipitation technique are spherical before and after encapsulation of CR. The disassociation pH, encapsulation efficiency, loading capacity and release properties of these polymers were found to depend on their backbone architecture and the amine type. By adjusting of these factors, such type of polymers hold promise as an interesting drug delivery vehicle. (C) 2011 Elsevier Ltd. All rights reserved.
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000291523600002
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/72021]
专题	中国科学院化学研究所
通讯作者	Gao Hui
作者单位	1.Tianjin Univ Technol, Sch Chem & Chem Engn, Tianjin 300384, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China 3.Nankai Univ, Inst Polymer Chem, Minist Educ, Key Lab Funct Polymer Mat, Tianjin 300071, Peoples R China
推荐引用方式 GB/T 7714	Gao Hui,Ma Yanan,Lu Xueyou,et al. PH-responsive nano-assemblies of amino poly(glycerol methacrylate)[J]. EUROPEAN POLYMER JOURNAL,2011,47(6):1232-1239.
APA	Gao Hui,Ma Yanan,Lu Xueyou,Liang Yongri,Chen Baoquan,&Ma Jianbiao.(2011).PH-responsive nano-assemblies of amino poly(glycerol methacrylate).EUROPEAN POLYMER JOURNAL,47(6),1232-1239.
MLA	Gao Hui,et al."PH-responsive nano-assemblies of amino poly(glycerol methacrylate)".EUROPEAN POLYMER JOURNAL 47.6(2011):1232-1239.