Hierarchical Self-Assembly of Bolaamphiphiles with a Hybrid Spacer and L-Glutamic Acid Headgroup: pH- and Surface-Triggered Hydrogels, Vesicles, Nanofibers, and Nanotubes

doi:10.1021/la103435t

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	Hierarchical Self-Assembly of Bolaamphiphiles with a Hybrid Spacer and L-Glutamic Acid Headgroup: pH- and Surface-Triggered Hydrogels, Vesicles, Nanofibers, and Nanotubes
	Wang, Tianyu 1; Jiang, Jian 1; Liu, Yu 2; Li, Zhibo 2; Liu, Minghua 1
刊名	LANGMUIR
	2010-12-21
卷号	26 期号:24 页码:18694-18700
ISSN号	0743-7463
DOI	10.1021/la103435t
英文摘要	Bolaamphiphiles with L-glutamic acid headgroups and hybrid linkers, each composed of two rigid benzene rings and different polymethylene units, were designed, and morphological controls of the hierarchical self-assemblies were realized via changing solution pH and application to solid surfaces. At a low pH of 3, bolaamphiphiles formed hydrogels with water and molecules with short and long spacers formed nanofibers and helical nanoribbon-nanotubes, respectively. In a pH 12 aqueous solution, vesicles were observed from cryo-TEM measurements for amphiphiles with short spacers that could transfer to huge vesicles when cast onto a mica surface. Amphiphiles with longer spacers self-assembled into nanoparticles in a pH 12 aqueous solution while micellar fibers were formed on a mica surface. Those assemblies were characterized with UV-vis, CD, and FT-IR spectroscopy and AFM and TEM observations. With molecular structure modification and the fine tuning of conditions, morphology transitions between various nanostructures were obtained from the self-assembled bolaamphiphiles. The environmental pH can induce different interaction modes between the headgroups, and at high pH, there are strong interactions between molecular assemblies and the mica surface. It is suggested that the active headgroups, rigid necks, and flexible linkers with different lengths render molecules with diverse aggregation morphologies.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000285217700020
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/70413]
专题	中国科学院化学研究所
通讯作者	Liu, Minghua
作者单位	1.Chinese Acad Sci, Inst Chem, CAS Key Lab Colloid Interface & Chem Thermodynam, Beijing Natl Lab Mol Sci BNLMS, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Chem, Joint Lab Polymer Sci & Mat, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Wang, Tianyu,Jiang, Jian,Liu, Yu,et al. Hierarchical Self-Assembly of Bolaamphiphiles with a Hybrid Spacer and L-Glutamic Acid Headgroup: pH- and Surface-Triggered Hydrogels, Vesicles, Nanofibers, and Nanotubes[J]. LANGMUIR,2010,26(24):18694-18700.
APA	Wang, Tianyu,Jiang, Jian,Liu, Yu,Li, Zhibo,&Liu, Minghua.(2010).Hierarchical Self-Assembly of Bolaamphiphiles with a Hybrid Spacer and L-Glutamic Acid Headgroup: pH- and Surface-Triggered Hydrogels, Vesicles, Nanofibers, and Nanotubes.LANGMUIR,26(24),18694-18700.
MLA	Wang, Tianyu,et al."Hierarchical Self-Assembly of Bolaamphiphiles with a Hybrid Spacer and L-Glutamic Acid Headgroup: pH- and Surface-Triggered Hydrogels, Vesicles, Nanofibers, and Nanotubes".LANGMUIR 26.24(2010):18694-18700.