Multi-armed poly(L-glutamic acid)-graft-oligoethylenimine copolymers as efficient nonviral gene delivery vectors

doi:10.1002/jgm.1405

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	Multi-armed poly(L-glutamic acid)-graft-oligoethylenimine copolymers as efficient nonviral gene delivery vectors
	Chen, Lei 1,2; Tian, Huayu 1; Chen, Jie 1; Chen, Xuesi 1; Huang, Yubin 1; Jing, Xiabin 1
刊名	JOURNAL OF GENE MEDICINE
	2010
卷号	12 期号:1 页码:64-76
关键词	Gene Therapy Nonviral Vector Oligoethylenimine Polyethylenimine Poly(L-glutamic Acid)
ISSN号	1099-498X
DOI	10.1002/jgm.1405
英文摘要	Background The application of polyethylenimine (PEI) in gene delivery has been severely limited by significant cytotoxicity that results from a nondegradable methylene backbone and high cationic charge density. It is therefore necessary to develop novel biodegradable PEI derivates for low-toxic, highly efficient gene delivery.
语种	英语
出版者	JOHN WILEY & SONS LTD
WOS记录号	WOS:000273895600007
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/69999]
专题	中国科学院化学研究所
通讯作者	Chen, Xuesi
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Chen, Lei,Tian, Huayu,Chen, Jie,et al. Multi-armed poly(L-glutamic acid)-graft-oligoethylenimine copolymers as efficient nonviral gene delivery vectors[J]. JOURNAL OF GENE MEDICINE,2010,12(1):64-76.
APA	Chen, Lei,Tian, Huayu,Chen, Jie,Chen, Xuesi,Huang, Yubin,&Jing, Xiabin.(2010).Multi-armed poly(L-glutamic acid)-graft-oligoethylenimine copolymers as efficient nonviral gene delivery vectors.JOURNAL OF GENE MEDICINE,12(1),64-76.
MLA	Chen, Lei,et al."Multi-armed poly(L-glutamic acid)-graft-oligoethylenimine copolymers as efficient nonviral gene delivery vectors".JOURNAL OF GENE MEDICINE 12.1(2010):64-76.