Switchable Wettability on Cooperative Dual-Responsive Poly-L-lysine Surface

doi:10.1021/la9041452

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	Switchable Wettability on Cooperative Dual-Responsive Poly-L-lysine Surface
	Guo, Yi 1,3; Xia, Fan 2; Xu, Li 3; Li, Jun 1; Yang, Wensheng 1; Jiang, Lei 2
刊名	LANGMUIR
	2010-01-19
卷号	26 期号:2 页码:1024-1028
ISSN号	0743-7463
DOI	10.1021/la9041452
英文摘要	A cooperative dual-responsive polypeptide surface switching between superhydrophilic and superhydrophobic states is presented. This macroscopic phenomenon of surface originates from the combination of the cooperative unfolding/aggregation of the poly-L-lysine (PLL) immobilized on the substrate with micro/nanocomposite structure in response to pH and temperature. At pH lower than the pK(a) of PLL (similar to 11.0), PLL mainly adopts a random coil conformation, which corresponds to the superhydrophilic state on the rough surface substrate. Raising the pH to higher than the pK(a) allows the appearance of alpha-helix conformation, which also corresponds to the hydrophilic state. However, heating up the surface at pH higher than the pK(a) destabilizes the alpha-helix conformation and induces the formation of aggregated beta-sheet structures, which represents the superhydrophobic state. Lowering the pH and temperature simultaneously switches a reversible conversion from superhydrophobic to superhydrophobic states. In the switching process, the hydrophobicity and hydrophilicity can be "memorized" due to the cooperative pH and temperature stimuli-induced unfolding/aggregation behaviors or PLL. This provides a new exciting prospect for understanding Surface propel-ties of polypeptides and the design of smart material surfaces with potential applications in nanodevices, bioseparation, and biosensors.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000273403400056
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/69701]
专题	中国科学院化学研究所
通讯作者	Yang, Wensheng
作者单位	1.Jilin Univ, Coll Chem, Key Lab Surface & Interface Chem Jilin Prov, Changchun 130012, Peoples R China 2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China 3.Jilin Univ, Minist Educ, Key Lab Mol Enzymol & Engn, Changchun 130021, Peoples R China
推荐引用方式 GB/T 7714	Guo, Yi,Xia, Fan,Xu, Li,et al. Switchable Wettability on Cooperative Dual-Responsive Poly-L-lysine Surface[J]. LANGMUIR,2010,26(2):1024-1028.
APA	Guo, Yi,Xia, Fan,Xu, Li,Li, Jun,Yang, Wensheng,&Jiang, Lei.(2010).Switchable Wettability on Cooperative Dual-Responsive Poly-L-lysine Surface.LANGMUIR,26(2),1024-1028.
MLA	Guo, Yi,et al."Switchable Wettability on Cooperative Dual-Responsive Poly-L-lysine Surface".LANGMUIR 26.2(2010):1024-1028.