Self-Assembly of Hyperbranched Multiarmed PEG-PEI-PLys(Z) Copolymer into Micelles, Rings, and Vesicles

doi:10.1021/la900932j

CORC > 化学研究所 > 中国科学院化学研究所

	Self-Assembly of Hyperbranched Multiarmed PEG-PEI-PLys(Z) Copolymer into Micelles, Rings, and Vesicles
	Guo, Zhaopei 1; Li, Yanhui 2; Tian, Huayu 1; Zhuang, Xiuli 1; Chen, Xuesi 1; Jing, Xiabin 1
刊名	LANGMUIR
	2009-09-01
卷号	25 期号:17 页码:9690-9696
ISSN号	0743-7463
DOI	10.1021/la900932j
英文摘要	Self-assembling of synthesized novel biodegradable hyperbranched amphiphilic poly(ethylene glycol)-polyethylenimine-poly(epsilon-benzyloxycarbonyl-L-lysine) (PEG-PEI-PLys(Z)) in aqueous media is studied. In aqueous media. PLys(Z) is the hydrophobic segment, with PEG and PEI as the hydrophilic segments. It will self-assemble into spherical shape when the selected solvent water is dropped into the common solvent tetrahydrofuran (THF). And when PEG-PEI-PLYS in common solvent is dropped into mixed solvent water and THF, rings will come into King. The spherical and rings are observed by environmental scanning electron microscopy (ESEM) and transmission electron microscopy ITEM). It shows that the size of the sphere is about 100 nm, and the diameter of ring distributes from 400 nm to 10 mu m and bigger with the time roll around. It also forms a large vesicle with a thick edge by another method, which is good for drug delivery.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000269197500012
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/66069]
专题	中国科学院化学研究所
通讯作者	Chen, Xuesi
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Changchun Univ Sci & Technol, Changchun 130022, Peoples R China
推荐引用方式 GB/T 7714	Guo, Zhaopei,Li, Yanhui,Tian, Huayu,et al. Self-Assembly of Hyperbranched Multiarmed PEG-PEI-PLys(Z) Copolymer into Micelles, Rings, and Vesicles[J]. LANGMUIR,2009,25(17):9690-9696.
APA	Guo, Zhaopei,Li, Yanhui,Tian, Huayu,Zhuang, Xiuli,Chen, Xuesi,&Jing, Xiabin.(2009).Self-Assembly of Hyperbranched Multiarmed PEG-PEI-PLys(Z) Copolymer into Micelles, Rings, and Vesicles.LANGMUIR,25(17),9690-9696.
MLA	Guo, Zhaopei,et al."Self-Assembly of Hyperbranched Multiarmed PEG-PEI-PLys(Z) Copolymer into Micelles, Rings, and Vesicles".LANGMUIR 25.17(2009):9690-9696.