Probing Protein Functions via Optical Single Molecule Detection

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	Probing Protein Functions via Optical Single Molecule Detection
	Li Xun ; Zhao Xin-Sheng 1
刊名	CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
	2008-12-10
卷号	29 期号:12 页码:2635-2642
关键词	Single Molecule Detection Protein Dynamic
ISSN号	0251-0790
英文摘要	In the last two decades, optical single molecule detection (SMD) has been rapidly developed as a powerful tool in many research fields, especially, in biological systems. This mini-review focuses on the application of SMD in protein studies. Based on the unique advantage, namely providing detailed distribution of molecular properties and tracking individual molecules in real time, SMD is applied to not only equilibrium yet heterogeneous systems such as protein folding, enzyme reaction dynamics, and membrane dynamics, but also non-equilibrium events. SMD plays an essential role in tracking the motion of protein motors in vivo.
语种	英语
出版者	HIGHER EDUCATION PRESS
WOS记录号	WOS:000262006900055
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/65693]
专题	中国科学院化学研究所
通讯作者	Zhao Xin-Sheng
作者单位	1.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci, State Key Lab Struct Chem Unstable Species, Beijing 100871, Peoples R China 2.Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem, Beijing 100871, Peoples R China
推荐引用方式 GB/T 7714	Li Xun,Zhao Xin-Sheng. Probing Protein Functions via Optical Single Molecule Detection[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2008,29(12):2635-2642.
APA	Li Xun,&Zhao Xin-Sheng.(2008).Probing Protein Functions via Optical Single Molecule Detection.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,29(12),2635-2642.
MLA	Li Xun,et al."Probing Protein Functions via Optical Single Molecule Detection".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 29.12(2008):2635-2642.