Synthesis of a New Water-Soluble Oligo(phenylenevinylene) Containing a Tyrosine Moiety for Tyrosinase Activity Detection

doi:10.1021/ol802210s

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	Synthesis of a New Water-Soluble Oligo(phenylenevinylene) Containing a Tyrosine Moiety for Tyrosinase Activity Detection
	Feng, Xuli; Feng, Fude; Yu, Minghui; He, Fang; Xu, Qingling; Tang, Hongwei; Wang, Shu; Li, Yuliang; Zhu, Daoben
刊名	ORGANIC LETTERS
	2008-12-04
卷号	10 期号:23 页码:5369-5372
ISSN号	1523-7060
DOI	10.1021/ol802210s
英文摘要	A new water-soluble oligo(phenylenevinylene) containing a tyrosine unit (OPV-Tyr) was synthesized as a fluorescent probe to optically detect tyrosinase activity. Upon the addition of tyrosinase, the tyrosine moiety was oxidized to quinone, which quenched the fluorescence of OPV-Tyr via intramolecular electron transfer from the phenylenevinylene unit to the quinone site. OPV-Tyr was elaborated to detect tyrosinase activity both in aqueous buffer solution and in agarose gel.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000261294300013
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/64065]
专题	中国科学院化学研究所
通讯作者	Wang, Shu
作者单位	Chinese Acad Sci, Key Lab Organ Solids, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Feng, Xuli,Feng, Fude,Yu, Minghui,et al. Synthesis of a New Water-Soluble Oligo(phenylenevinylene) Containing a Tyrosine Moiety for Tyrosinase Activity Detection[J]. ORGANIC LETTERS,2008,10(23):5369-5372.
APA	Feng, Xuli.,Feng, Fude.,Yu, Minghui.,He, Fang.,Xu, Qingling.,...&Zhu, Daoben.(2008).Synthesis of a New Water-Soluble Oligo(phenylenevinylene) Containing a Tyrosine Moiety for Tyrosinase Activity Detection.ORGANIC LETTERS,10(23),5369-5372.
MLA	Feng, Xuli,et al."Synthesis of a New Water-Soluble Oligo(phenylenevinylene) Containing a Tyrosine Moiety for Tyrosinase Activity Detection".ORGANIC LETTERS 10.23(2008):5369-5372.