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Biodistribution of pristine single-walled carbon nanotubes in vivo
Yang, Sheng-Tao; Guo, Wei; Lin, Yi; Deng, Xiao-Yong; Wang, Hai-Fang; Sun, Hong-Fang; Liu, Yuan-Fang; Wang, Xin; Wang, Wei; Chen, Min
刊名JOURNAL OF PHYSICAL CHEMISTRY C
2007-12-06
卷号111期号:48页码:17761-17764
ISSN号1932-7447
DOI10.1021/jp070712c
英文摘要The biodistribution of pristine single-walled carbon nanotubes (SWNTs) in mice was determined by using the skeleton C-13-enriched SWNTs and isotope ratio mass spectroscopy. The results suggested that the SWNTs were distributed in the entire body, with major accumulations in the liver, lungs, and spleen over an extended period of time. The specimen from the effected organ tissues were examined by using transmission electron microscopy, aimed toward an understanding of the possible uptake mechanism. The biological consequence of pristine SWNTs is obviously very different from that of their chemically modified or functionalized counterparts. The implication of such a fact is discussed.
语种英语
出版者AMER CHEMICAL SOC
WOS记录号WOS:000251291900015
内容类型期刊论文
源URL[http://ir.iccas.ac.cn/handle/121111/61457]  
专题中国科学院化学研究所
通讯作者Sun, Hong-Fang
作者单位1.Peking Univ, Beijing Natl Lab Mol Sci, Coll Chem & Mol Engn, Dept Biol Chem, Beijing 100871, Peoples R China
2.Clemson Univ, Dept Chem, Clemson, SC 29634 USA
3.Clemson Univ, Lab Emerging Mat & Technol, Clemson, SC 29634 USA
4.Shanghai Univ, Int Nanochem & Nanobiol, Shanghai 200444, Peoples R China
5.Xiamen Univ, Dept Oceanog, Lab Mass Spectrometry, Xiamen 361005, Peoples R China
推荐引用方式
GB/T 7714
Yang, Sheng-Tao,Guo, Wei,Lin, Yi,et al. Biodistribution of pristine single-walled carbon nanotubes in vivo[J]. JOURNAL OF PHYSICAL CHEMISTRY C,2007,111(48):17761-17764.
APA Yang, Sheng-Tao.,Guo, Wei.,Lin, Yi.,Deng, Xiao-Yong.,Wang, Hai-Fang.,...&Sun, Ya-Ping.(2007).Biodistribution of pristine single-walled carbon nanotubes in vivo.JOURNAL OF PHYSICAL CHEMISTRY C,111(48),17761-17764.
MLA Yang, Sheng-Tao,et al."Biodistribution of pristine single-walled carbon nanotubes in vivo".JOURNAL OF PHYSICAL CHEMISTRY C 111.48(2007):17761-17764.
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